ID A0A1W2TQY7_ROSNE Unreviewed; 484 AA.
AC A0A1W2TQY7;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=tRNA (guanine(9)-N1)-methyltransferase {ECO:0000256|ARBA:ARBA00020451};
DE EC=2.1.1.221 {ECO:0000256|ARBA:ARBA00012797};
DE AltName: Full=tRNA methyltransferase 10 {ECO:0000256|ARBA:ARBA00032166};
DE AltName: Full=tRNA(m1G9)-methyltransferase {ECO:0000256|ARBA:ARBA00031792};
GN ORFNames=SAMD00023353_5500240 {ECO:0000313|EMBL:GAP90845.1};
OS Rosellinia necatrix (White root-rot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP90845.1};
RN [1] {ECO:0000313|EMBL:GAP90845.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W97 {ECO:0000313|EMBL:GAP90845.1};
RA Kanematsu S.;
RT "Draft genome sequence of Rosellinia necatrix.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=guanosine(9) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-
CC methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:43156, Rhea:RHEA-COMP:10367, Rhea:RHEA-COMP:10368,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:73542, ChEBI:CHEBI:74269; EC=2.1.1.221;
CC Evidence={ECO:0000256|ARBA:ARBA00000855};
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DR EMBL; DF977500; GAP90845.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W2TQY7; -.
DR STRING; 77044.A0A1W2TQY7; -.
DR OMA; TAWTETR; -.
DR OrthoDB; 2908056at2759; -.
DR Proteomes; UP000054516; Unassembled WGS sequence.
DR GO; GO:0052905; F:tRNA (guanosine(9)-N1)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd18089; SPOUT_Trm10-like; 1.
DR Gene3D; 3.40.1280.30; -; 1.
DR InterPro; IPR028564; MT_TRM10-typ.
DR InterPro; IPR038459; MT_TRM10-typ_sf.
DR InterPro; IPR007356; tRNA_m1G_MeTrfase_euk.
DR InterPro; IPR016009; tRNA_MeTrfase_TRMD/TRM10.
DR PANTHER; PTHR13563; TRNA (GUANINE-9-) METHYLTRANSFERASE; 1.
DR PANTHER; PTHR13563:SF13; TRNA METHYLTRANSFERASE 10 HOMOLOG A; 1.
DR Pfam; PF01746; tRNA_m1G_MT; 1.
DR PROSITE; PS51675; SAM_MT_TRM10; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:GAP90845.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054516};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:GAP90845.1}.
FT DOMAIN 145..389
FT /note="SAM-dependent MTase TRM10-type"
FT /evidence="ECO:0000259|PROSITE:PS51675"
FT REGION 1..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 484 AA; 53811 MW; E76A61166673887E CRC64;
MEAPEGMLPA PATDERSGVN NKDESNHGAD IGNRPSGSRG TKRSIEDDHH CTDDEGGEDD
ENDQTSRDID ASRLVAVPDE AVPMTKSRMK KLKRQKKWEE AREGRRLKRR DKRHDRQARK
RVEREEEIAT AVAEGRDPVL NADRRRNKSR RGIQVPVAVI VDCQFETYMQ EQELISLSSQ
LTRCYSDNRG AQHSVHLYIS SFGGLLKERY ETVLENQHLK WKGISLCEGD FVQAANQAKE
CMSGPNSGEL IDVLQQSTSA GPVSFASAAP TNTKKARLAP TPEPEAEDVD KSIVYLTADS
PYTLDRLEPN TCYVVGGIID KNREKGLCYR IARGKNVRTA KLPIGEYMVL QHRHILATNH
VVEIMLKWLE TGDWGAAFMQ VIPTRKGGQL KTDEGTPTRI VEGLVENLKD VEAEGDTKQV
DNSKSQSTSQ NAAQNAGDAM EVEGDNAEEG LARNSLDEPR WSAPPLEIET METEKEHPAN
GMVG
//
