ID   A0A1W2TR05_ROSNE        Unreviewed;       359 AA.
AC   A0A1W2TR05;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Putative duf1295 domain-containing protein {ECO:0000313|EMBL:GAP90890.1};
GN   ORFNames=SAMD00023353_5500750 {ECO:0000313|EMBL:GAP90890.1};
OS   Rosellinia necatrix (White root-rot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Xylariaceae; Rosellinia.
OX   NCBI_TaxID=77044 {ECO:0000313|EMBL:GAP90890.1};
RN   [1] {ECO:0000313|EMBL:GAP90890.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W97 {ECO:0000313|EMBL:GAP90890.1};
RA   Kanematsu S.;
RT   "Draft genome sequence of Rosellinia necatrix.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; DF977500; GAP90890.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2TR05; -.
DR   OMA; LNAWWSA; -.
DR   OrthoDB; 38588at2759; -.
DR   Proteomes; UP000054516; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.120.1630; -; 1.
DR   InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR   InterPro; IPR010721; UstE-like.
DR   PANTHER; PTHR32251; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR   PANTHER; PTHR32251:SF15; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295); 1.
DR   Pfam; PF06966; DUF1295; 1.
DR   PROSITE; PS50244; S5A_REDUCTASE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054516};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          208..268
FT                   /note="Steroid 5-alpha reductase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50244"
SQ   SEQUENCE   359 AA;  40082 MW;  4E697139D2FBD026 CRC64;
     MSYPGDLSRY GGRSYNTSGG VLHPSPVPST VSYHIPIQRE LLDVGIFKDT ILPSLQLHAP
     LALVAYGIGR ATNSVEAKDW LWPIAPVVNG WWSAVGRKVY RRGLTFGQAF ATLSRPERLL
     LTGVTLWGGR LFYRVASRSI RRRRRGKGDD NPRYGAEKLE KGYWNKALFT SFLPEALIQT
     IISLPVTAPF HHQGAVLTGY HPAVQALAVG LFCAGFTLEV VADAQLEKFK DSGRDSTSVY
     KEGVWSLVRH PNYLGDALVH LSFPLLLYGS DMLAPVEVLG GIANYVFLRY VGGDKQTERH
     QTRRYSETNP EKFADFQRLK ETHNSFWPKA DVLTNRWLWI VVGAGTVGAA VEQVFHHVF
//