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Database: UniProt
Entry: A0A1W4V2Y5_DROFC
LinkDB: A0A1W4V2Y5_DROFC
Original site: A0A1W4V2Y5_DROFC 
ID   A0A1W4V2Y5_DROFC        Unreviewed;       547 AA.
AC   A0A1W4V2Y5;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   31-JUL-2019, entry version 13.
DE   SubName: Full=G protein-activated inward rectifier potassium channel 3 isoform X5 {ECO:0000313|RefSeq:XP_017046396.1};
GN   Name=LOC108091616 {ECO:0000313|RefSeq:XP_017046396.1};
OS   Drosophila ficusphila (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=30025 {ECO:0000313|Proteomes:UP000192221, ECO:0000313|RefSeq:XP_017046396.1};
RN   [1] {ECO:0000313|RefSeq:XP_017046396.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (APR-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_017046396.1; XM_017190907.1.
DR   SMR; A0A1W4V2Y5; -.
DR   GeneID; 108091616; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000192221; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000192221};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_017046396.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192221};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     78    101       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    121    144       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    164    188       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       40    193       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      200    373       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      516    547       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   547 AA;  60950 MW;  291B74CE2234D838 CRC64;
     MLFFIGLVCL VCLSSVLLQA MIWYRQTRFS SRRVRKRVVF KHGECNVVQG NVAKRRRRYL
     QFFFQDIFTT LVDAQWRWTL LVFAASFVFS WAFFGFIWWI IAYAHNDLEY TILKNNSPDL
     VANMTHTVCV TQVSNMMSAF LYSVETQTTI GYGNRYVTEE CPEAIFTMCI QCITGVFIQA
     FMVGIVFAKL SRPKKRAQTL LFSRNAVICH RDGVPCLMFR VGDMRKSHII EAHIRAQIIR
     KKVTKEGEVL PFFQQELHIG ADGGEDRLMF IWPTTIVHKI DRNSPLYMLS ASDMLKERFE
     VVVMLEGVIE STGMTTQARS SYLPSEVLWG HRFVNVVSFR KETGEYEVDY TLFNNTYDVD
     TPLCSAKQLD ELKSEYTKSA KSCPGLGVNA PFADRTLSAS MFQRIASAAS VDHLDPASDE
     SLDSGRLQIR SHSIPNGVLA SELEPLNNNK HGASFTMGGL TITTTAPSIP NLSSINEKTN
     SGNSINSSNY SNNNSLSTLT GGGSAASGPG GGITIVAGSG NNGGGKHKSN PRRLSIKQDQ
     LPIDSIC
//
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