ID A0A1W4W412_AGRPL Unreviewed; 492 AA.
AC A0A1W4W412;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=KDEL motif-containing protein 1 isoform X1 {ECO:0000313|RefSeq:XP_018318879.1};
GN Name=LOC108732520 {ECO:0000313|RefSeq:XP_018318879.1};
OS Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018318879.1};
RN [1] {ECO:0000313|RefSeq:XP_018318879.1}
RP IDENTIFICATION.
RC TISSUE=Entire body {ECO:0000313|RefSeq:XP_018318879.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-seryl-[EGF-like domain protein] + UDP-alpha-D-glucose = 3-O-
CC (beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP;
CC Xref=Rhea:RHEA:58116, Rhea:RHEA-COMP:14610, Rhea:RHEA-COMP:16010,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:58885, ChEBI:CHEBI:140576;
CC Evidence={ECO:0000256|ARBA:ARBA00000570};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-
CC (beta-D-xylosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP;
CC Xref=Rhea:RHEA:62016, Rhea:RHEA-COMP:16010, Rhea:RHEA-COMP:16011,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:57632,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:132085;
CC Evidence={ECO:0000256|ARBA:ARBA00000273};
CC -!- SIMILARITY: Belongs to the KDELC family.
CC {ECO:0000256|ARBA:ARBA00006063}.
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DR RefSeq; XP_018318879.1; XM_018463377.1.
DR AlphaFoldDB; A0A1W4W412; -.
DR STRING; 224129.A0A1W4W412; -.
DR EnsemblMetazoa; XM_018463377.1; XP_018318879.1; LOC108732520.
DR GeneID; 108732520; -.
DR KEGG; apln:108732520; -.
DR InParanoid; A0A1W4W412; -.
DR OrthoDB; 1826823at2759; -.
DR Proteomes; UP000192223; Unplaced.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR006598; CAP10.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR12203:SF122; CAP10 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12203; KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED; 1.
DR Pfam; PF00630; Filamin; 1.
DR Pfam; PF05686; Glyco_transf_90; 1.
DR SMART; SM00672; CAP10; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50194; FILAMIN_REPEAT; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000192223};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..492
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010742017"
FT REPEAT 18..124
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT DOMAIN 222..464
FT /note="Glycosyl transferase CAP10"
FT /evidence="ECO:0000259|SMART:SM00672"
SQ SEQUENCE 492 AA; 57944 MW; 1BFECBA64BE8B8BD CRC64;
MKLNIYCLIM KIIIFNCIVY VDASEYKIWG PGLKPEIVMP ARYFFIESIP NCDTNLLELI
DLDIKIEGSK IDSNKPCRIW TNILNRNDGS YIVRYKLYEP CINVKIDIKV RGENIKGFPL
TFKYIMFSED CNCNIHNVSS FINNWECGET QTQIKEDLHL FKGIDFGKIR KRIVSTYDNP
GAVSLCNYVI KNNLIYRKCY GQHVGFKMFM DNILLSLTRK VLLPDFEMFV NLGDWPLVKD
TNEIFPIFSW CGSKDSFDIV MPTYDITEST LESMGRVMLD MLSVQGNVRD KWENRHPKIF
WRGRDSSRER LKLIEISRQY PDLFNVSLTN FFFFRNEMEK YGPTSKHVSF YDFFDYKYQI
NLDGTVAAYR FPYLLAGGSL VFKQDSKYYE FFYNNLKSNM HYIPIKQDLS DLIEKIKWAV
ENDEEAKTIG MHGRDFANDN LLPKNIFCYH VQLFNEYSKK VTSTVEIVEG MEMVKSSRRE
KCNCNYNMKD EL
//
