ID A0A1W4WDN1_AGRPL Unreviewed; 559 AA.
AC A0A1W4WDN1;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 26 {ECO:0000256|ARBA:ARBA00019686};
DE AltName: Full=Mediator complex subunit 26 {ECO:0000256|ARBA:ARBA00031968};
GN Name=LOC108734843 {ECO:0000313|RefSeq:XP_018322049.1};
OS Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018322049.1};
RN [1] {ECO:0000313|RefSeq:XP_018322049.1}
RP IDENTIFICATION.
RC TISSUE=Entire body {ECO:0000313|RefSeq:XP_018322049.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 26 family.
CC {ECO:0000256|ARBA:ARBA00009681}.
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DR RefSeq; XP_018322049.1; XM_018466547.2.
DR AlphaFoldDB; A0A1W4WDN1; -.
DR STRING; 224129.A0A1W4WDN1; -.
DR EnsemblMetazoa; XM_018466547.2; XP_018322049.1; LOC108734843.
DR GeneID; 108734843; -.
DR KEGG; apln:108734843; -.
DR InParanoid; A0A1W4WDN1; -.
DR OrthoDB; 4048705at2759; -.
DR Proteomes; UP000192223; Unplaced.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00183; TFIIS_I; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR042376; MED26.
DR InterPro; IPR003617; TFIIS/CRSP70_N_sub.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR15201; CRSP70; 1.
DR PANTHER; PTHR15201:SF1; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26; 1.
DR Pfam; PF08711; Med26; 1.
DR SMART; SM00509; TFS2N; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000192223}.
FT DOMAIN 7..84
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 85..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 62627 MW; 45BAD339770FE8F7 CRC64;
MQNNVTELTQ KLLRALDSNY NVIDMPAVIE IISLLEKVAI TKELLETTRV GKHVNELRRN
TSNESLAKRA KELVKKWRSM VIPGSNGQIK SNLSSPGELS ASEDLQNKKR VAKEAIENAI
IKRPKVNGQV SELDFSDNSN SSFKDVINSS NSSTSTTNKI FSKRDAINAN SDSNSSLPDA
KQDPLLEQQQ PKKRGRKKGS KNHKNLLDEA ETSFSNKLNV SRGNAKVKTT KELLADLQIK
SGNAVLPACK PIEDLNERAA KLTERVSIID QKLNATSNRY KNSQKKLSYG QKNSSSERVI
ESGSFSNVKS TSSEKPLPHS PNSSASDDEI IVVDDEEKNS KSEYAEVPVV EDVPKSLSEE
EALAQLPPID KSVLEEFEEH LCYCQLVENK TDFSVEEDDA DVNLQHTYEF VENSNCPART
YLEEKYHLGE ACLEDKVTLL HTTNMPNVNG NYSIGGSKTE SEMLENELYV NVVPSVNKES
IPKVFNSEDF REPASENYKK YSISKEDEKS DTCEVETLEK SGDDERPNCC ETFKEWHEVV
ETRSYNGEIL KILPYVIID
//
