ID A0A1W4WQ99_AGRPL Unreviewed; 629 AA.
AC A0A1W4WQ99;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X2 {ECO:0000313|RefSeq:XP_018322652.1};
GN Name=LOC108735264 {ECO:0000313|RefSeq:XP_018322652.1};
OS Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018322652.1};
RN [1] {ECO:0000313|RefSeq:XP_018322652.1}
RP IDENTIFICATION.
RC TISSUE=Entire body {ECO:0000313|RefSeq:XP_018322652.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_018322652.1; XM_018467150.1.
DR AlphaFoldDB; A0A1W4WQ99; -.
DR EnsemblMetazoa; XM_018467150.1; XP_018322652.1; LOC108735264.
DR GeneID; 108735264; -.
DR OrthoDB; 2902917at2759; -.
DR Proteomes; UP000192223; Unplaced.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 2.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR10316:SF40; LD27118P; 1.
DR PANTHER; PTHR10316; MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED; 1.
DR Pfam; PF00595; PDZ; 2.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00228; PDZ; 2.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50106; PDZ; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Kinase {ECO:0000313|RefSeq:XP_018322652.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000192223};
KW Transferase {ECO:0000313|RefSeq:XP_018322652.1}.
FT DOMAIN 50..83
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 97..130
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 162..232
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 327..390
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 71524 MW; A434256B5FED7F82 CRC64;
MSHKSDNSSL SQPLRVETEG DSVSSTNSNF GEEDKERFNG HTEEDTNDLG PLPPKWEKAY
TESGEVYFID HSTGTSHWLD PRLSKFQKKS LEDCMDDELP YGWEKISDPH YGIYFIDHVN
RRTQYENPVI QAKRAAAQAS TSSISRLPFT KDPVELCGQR ITTSLVKSSR GLGFTIIGGD
DGVDEFLQIK SVVPKGPAWL DGKLEMGDVI VYVNDICVLG YTHNQIVRLF QSISVGSTVS
LEVCRGYPLP FDPNDPNTEV VTTIAVDDNL QVVSVEKQLS SLESKYNFLD RNDNNRSETN
SNQESVHDID NILKEINKLN VGKLEVTVKI VKGNLGFGFT IADSACGQRV KKILDRHRCK
NLQEGDILLE INNINLQNMT HDKVVQVLKN CPYSSEATIC VQRNYCNKNS NIRNKPRKND
NRLIGKEKND RSKTPTADIY CTQTREVLPA RPKTPLIDTR HQTKSPVKDL DHSTDEIMKR
DLHNENFKQD SATGLRLSLI DNTEVDDEDL LLRSEKFNQA PPYYNKFQDC HYYDNYNYYK
NVENGSLYDF SGIKKSVSQD WWVLPHNSEY IETAVTLNRH DTGFGFRIIG GIEDRSQTRI
LVETDSALYW EAVNVGRLLK TCYLVMART
//
