ID   A0A1W4WRM2_AGRPL        Unreviewed;      1328 AA.
AC   A0A1W4WRM2;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=FH1/FH2 domain-containing protein 3 isoform X7 {ECO:0000313|RefSeq:XP_018323142.1};
GN   Name=LOC108735605 {ECO:0000313|RefSeq:XP_018323142.1};
OS   Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC   Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX   NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018323142.1};
RN   [1] {ECO:0000313|RefSeq:XP_018323142.1}
RP   IDENTIFICATION.
RC   TISSUE=Entire body {ECO:0000313|RefSeq:XP_018323142.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_018323142.1; XM_018467640.1.
DR   EnsemblMetazoa; XM_018467640.1; XP_018323142.1; LOC108735605.
DR   GeneID; 108735605; -.
DR   OrthoDB; 2918313at2759; -.
DR   Proteomes; UP000192223; Unplaced.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR041387; FHOD1_GBD_N.
DR   InterPro; IPR014768; GBD/FH3_dom.
DR   PANTHER; PTHR45920; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR   PANTHER; PTHR45920:SF4; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR   Pfam; PF02181; FH2; 1.
DR   Pfam; PF18382; Formin_GBD_N; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS51232; GBD_FH3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000192223}.
FT   DOMAIN          126..497
FT                   /note="GBD/FH3"
FT                   /evidence="ECO:0000259|PROSITE:PS51232"
FT   DOMAIN          815..1208
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          10..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          427..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1280..1303
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        427..441
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        444..463
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        502..518
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1328 AA;  150989 MW;  ECB9812E2A89C1C4 CRC64;
     MKSCKKYLKE QQQQPQYHHR HYHHPQTRVN NNTNNLNVSV GSSTRVGHAG KVSHNTETYN
     INGIPFGSGS ENAFDTNAMA FTCRVQYLND IDPFSYTTNI PDPSRPPLHT FSITLPLINQ
     LAAVHRILNA PHRLDDVAIQ LYKDGDYGAY LDLDASISEQ NEEFEGFQSN KKNSLVLRTQ
     LSVRVHTIIE KLLTSEGRDL RRALFSLKQI FQEDKDLVHE FVQNDGLACL IKVGSEADQN
     YQNYILRALG QVMLYVDGMN GVIQHNETVQ WLYSLISSKF RLVVKTALKL LLVFVEYTET
     NCMLLIKAVE IVDCSHGLQP WSNVMKLLKD FDSADTELLI YAMTLINKCF NGIPDQDTYY
     DQTDSLEEQG IEAIIQRYMS KPGTDLDLLQ QFQIYEAVLQ YEDDDEDKGI PLRHLDESFR
     KTLRNRKSVI ESSERRKSRR HSTGTAPVHT SLSQTLRNHL ETFNLSNNED DDNDESSAGP
     EDVRLSGSCN IEKSKANDVG VTPALRRRRE RAERQRSFMR EQQESAALLR GCFVSQHENS
     DNKTFTNNNN NINNNNGSMS PGGTYGNGQR LINGNIVNKI PNRKDLAYMN SVNKLDTEEN
     SVGLMNKKPW ILSMMYNGKK PPDEQQSYDN IEDIENVNEN DRKTILQIKK ENTVKDLTQK
     LSSQNILQSP TEEKVNRIGD MSGLISKAKE GLAKSKSNAL IKSPTSESLP KLETKKTENE
     LRWEELAKSL NRSLNLCDID FTDLTSDDEN DILAPALPAT GIPPPPPPLI TNMGIAIGAP
     PPPPLNNRIS PPTPPNAPIF GSNIQKSSSK LTTESKIPIK KNKKTVKLFW KEVRDDPITS
     IKLKTGLIWD ELTPVTVDTQ KLEHLFESRA KDLITKKQQE LNKNKEIIVL DPKRSNAINI
     GMTKLPPPRS IKTAILKMDA TIMNREGIEK LLTMLPTEEE RTKIQEAQAS NPDLPLGSAE
     QFLLTLASIS ELPARLKLWA FKLDFENTER EIAEPLMDLK QGIEILRMNK TFRGILSTLL
     SIGIFLNGTE VKGFQIEYLS KVPEVKDTVH KHSLLHHLCH ILMEKFPEAS DLYSEIGAIT
     RASKIDFDEL MLNIQRLEAD CKASWDHLKL IAKHDGSTMM KVKMSDFLTD CAERIIILSI
     IHRRIINRFH KFLLWLGIPL HQIVDTKPNE FCKTISEFAL EYRTTRERVL QQLEKKANHR
     ERNKTRGKMI TEIGKFRSKE DRADAELRQL LGSDISDVES LQGTLPWRRR GKDTRTSLLS
     QANGNLTDGD DEILESLVKT ATKGPSSRTA PRERKRTRHA DRKSLRRTLK NGLSEEEKKH
     LSTYIKSY
//