ID A0A1W4X1L9_AGRPL Unreviewed; 584 AA.
AC A0A1W4X1L9;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Protein cueball {ECO:0000256|ARBA:ARBA00040020};
GN Name=LOC108737718 {ECO:0000313|RefSeq:XP_018326293.1};
OS Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018326293.1};
RN [1] {ECO:0000313|RefSeq:XP_018326293.1}
RP IDENTIFICATION.
RC TISSUE=Entire body {ECO:0000313|RefSeq:XP_018326293.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cueball family.
CC {ECO:0000256|ARBA:ARBA00038070}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_018326293.1; XM_018470791.2.
DR AlphaFoldDB; A0A1W4X1L9; -.
DR STRING; 224129.A0A1W4X1L9; -.
DR EnsemblMetazoa; XM_018470791.2; XP_018326293.1; LOC108737718.
DR GeneID; 108737718; -.
DR KEGG; apln:108737718; -.
DR InParanoid; A0A1W4X1L9; -.
DR OrthoDB; 3662245at2759; -.
DR Proteomes; UP000192223; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR PANTHER; PTHR46513:SF39; PROTEIN CUEBALL; 1.
DR PANTHER; PTHR46513; VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED; 1.
DR Pfam; PF00058; Ldl_recept_b; 2.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00135; LY; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF63825; YWTD domain; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS51120; LDLRB; 2.
PE 3: Inferred from homology;
KW Differentiation {ECO:0000256|ARBA:ARBA00022943};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oogenesis {ECO:0000256|ARBA:ARBA00022943};
KW Reference proteome {ECO:0000313|Proteomes:UP000192223};
KW Signal {ECO:0000256|SAM:SignalP};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..584
FT /note="Protein cueball"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010725469"
FT TRANSMEM 483..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 156..200
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 201..246
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 382..420
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 386..396
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 410..419
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 584 AA; 66414 MW; 4844B3D76CE58D87 CRC64;
MLIKLGAILL VSAVSSAHMI SQRWDVAVAV GDEIKLLNYT GSLLGTAVEQ FTKLKALSYD
YVRHQFLVSN MEKLNDTIFK IQLNNKQTAI VPIVKDLPDD VQGIAIDPLT DILYWTDSDN
RSINYVSLKH SSDKLNNLLY FKDEIPHDIA VDSCKRYLYW TNLNIMKPSV ARISLNTMKQ
EVLVSDDLFS PTGITIDYEN DRIYWGDLRQ GIYFRIESTK MDGTERQILF EGTHQKPYGV
AVDSDYVYWT DVINNELNRK SKHDDSPPEC IHKFDAIPQG VVVHDTGFVQ REECKDVYNA
IENFKGTTTE FFLANEEKNE SNECLKRGEF IDGGCQCHRG YTGTNCEISL CYNFCVHGEC
HFTSLAYPQC KCPPGFMGAR CQKNICDGFC LNDGKCSIAA NSTSTPICKC TNGFSGIRCQ
ESTEFSKICE LYCSRRHASS LLDEESEMLC KCQDGSFKIV DNSVRVQESA EQTSIWQYTE
KPAIIVLSVC MVVMFVLIIV LASFVCKLRR RPRIKKRIIV NKNVTPLTYR PQAPEQCEIT
IENCCNMNVC ETPCFEPPKL RAFHSKKEEK KELLGNMENG EDLY
//
