ID A0A1W4X5V5_AGRPL Unreviewed; 775 AA.
AC A0A1W4X5V5;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Venom dipeptidyl peptidase 4 isoform X3 {ECO:0000313|RefSeq:XP_018327766.1, ECO:0000313|RefSeq:XP_018327767.1};
GN Name=LOC108738717 {ECO:0000313|RefSeq:XP_018327766.1,
GN ECO:0000313|RefSeq:XP_018327767.1, ECO:0000313|RefSeq:XP_018327768.1};
OS Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018327768.1};
RN [1] {ECO:0000313|RefSeq:XP_018327766.1, ECO:0000313|RefSeq:XP_018327767.1}
RP IDENTIFICATION.
RC TISSUE=Entire body {ECO:0000313|RefSeq:XP_018327766.1,
RC ECO:0000313|RefSeq:XP_018327767.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_018327766.1; XM_018472264.2.
DR RefSeq; XP_018327767.1; XM_018472265.1.
DR RefSeq; XP_018327768.1; XM_018472266.1.
DR EnsemblMetazoa; XM_018472264.2; XP_018327766.1; LOC108738717.
DR EnsemblMetazoa; XM_018472265.1; XP_018327767.1; LOC108738717.
DR EnsemblMetazoa; XM_018472266.1; XP_018327768.1; LOC108738717.
DR GeneID; 108738717; -.
DR OrthoDB; 2876738at2759; -.
DR Proteomes; UP000192223; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF192; IP17501P; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000192223};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 112..486
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 570..773
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 775 AA; 86486 MW; 6ADD6B8E33213975 CRC64;
MEKRHGKNKI LFISLAVGIV IVAAVIVILV IFLKNKGDSN ADNQDFAITL EEILYGSLAA
SGFNATWISG SELFFRSSEG DVLLYNVETA TTRTLLSGNS SVLATAFDYF LSPDRNYLLI
GHDYQKLYRY SFLAQYTIVN LLNQQTKLVN VSGESILQLA SWGPVGNSLI FIMRNNIYYR
ASAASEEDTQ ITTDGSIGNV YNGVPDWVYE EEVFSSNKAF WFSPDGTKLA YAKFDDRNVP
LMTIPVYGLP GDLNFQYTRA VQIRYPKAGT VNPTVTFHVV NLQNQFSQLI LSPPDALRNV
DNILATVNWA TNTTVTAIWM NRVQNYAEIL AYVISDTVAT SETIVSINKT NGWIELFTPP
LFSDDGTKMA VILSQDQGNN LGGYRHITLF NVNQTSSANV ITNGKFVVGE ILSWDSNNNL
IYYTSNTEED PAVQHVYSVS TVSKNRTCLS CNTDQSSLST DCLYNSADFS LDHTHFALKC
EGPGVPQISI FRTNNQHVTD WTNGDELKSK LRNKSIPTIK QMSFEVAGGF VAQVLLKLPP
NLDTSGNVKY PMVVHVYGGP DSYQVIKKYS MDWGSYLASN KSIIYAMIDG RGSGLKGDKM
LFSLYRALGT VEVSDQINVT RQIQLSLPYV DSSKTAIWGW SYGGYASAMA LAKDVDGVFK
CGMSVAPVTD WTLYDSVYTE RFMGLPLPGD NSEGYKNSLL LSQYEGIRKK DYFLIHGTLD
DNVHYQQSML WAKVLEQQDI LFRQLSYPDE DHGLATIRPH LYHSLENFLN ECFLL
//
