ID A0A1W4X877_AGRPL Unreviewed; 1362 AA.
AC A0A1W4X877;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Neogenin isoform X2 {ECO:0000313|RefSeq:XP_018329042.1};
GN Name=LOC108739561 {ECO:0000313|RefSeq:XP_018329042.1};
OS Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018329042.1};
RN [1] {ECO:0000313|RefSeq:XP_018329042.1}
RP IDENTIFICATION.
RC TISSUE=Entire body {ECO:0000313|RefSeq:XP_018329042.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. DCC family.
CC {ECO:0000256|ARBA:ARBA00009588}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_018329042.1; XM_018473540.2.
DR EnsemblMetazoa; XM_018473540.2; XP_018329042.1; LOC108739561.
DR GeneID; 108739561; -.
DR OrthoDB; 5398621at2759; -.
DR Proteomes; UP000192223; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00063; FN3; 6.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR010560; Neogenin_C.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF06583; Neogenin_C; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 3: Inferred from homology;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000192223};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1034..1058
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..119
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 121..220
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 240..329
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 334..421
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 438..531
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 537..630
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 632..725
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 732..827
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 835..930
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 933..1030
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1260..1286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1362 AA; 150624 MW; 3B05A02BCE64B6EF CRC64;
MINKLYDTMR TNSGCFILKK YVHVLIVTSV LTHIQAYIVE FIIEPADTTV EAGQSCVLDC
VVKTAQEYPS NMVTIQWLDQ DRQPLSYLGD FYRSQLANGS LYIASVSEEL SGNYQCLASL
PNVGAVVSRV AHLTIATLSG FLQEPRDITV YPGQKAYFAC RVQTSLPPRI RWLKDERPLQ
LDKLRMAILP SGALEIDEVK SADQGSYRCN VSSVNTYRLS NKANLIINED QEQAASISAP
SFIALPQSKI VKEGETVTLD CTANGNPYPT ITWLKDGYTV DMANLDSRFS WVGSTTSLQI
KKIEESDAGV YQCRAENRED SVDASVTLQV QVPPKFLKKP MDKVDVINKD TEFECSVYGK
PEPKIEWLKN GEIIIPTEYY QIVNGNNLKI LGLMTSDSGL FQCIASNPAG NIQASASLKV
TSAADGDEKN VQEEVPGPPI NLKASIVKAR FVTLSWQPPP NYNGDIIAYS VYYKRGSSER
ERVQNTTRSR LEDINIGGLQ PGQVYFFRVV AYSKLGPGLS SESLKVTTQT EERVPSAPEQ
FNAYATSVMS IHATWKPPLV QNGEIQLYRV YYMETMSSTE HNIETTNLQC DILGLSIYTE
YSVWVVAINQ NGAGAASEEK LVRTFSAPPS ESPLNVTLEP ASSTSIIVYW EPPAPDGQNG
IITGYKLRYR KLGRKGDTIT TPANLRSFTL SNLEKGSTYQ VKLWALNVNG TGPPTEWYEC
QTLENDSDES QVPDIPTQLR VRAHSDKIGV MWNAPLNQNI KVRNYILGWG KGVSDIYTKE
LDEKQRSYVI EKLEPNSDYV ISLRASNQKG AGLQLYANVR TRDEPPPEIV SPLIPPVGLK
AQVLSSSSVV LYWTDTSLSK SQYVRDRYYV VKFTAEKSSK SKYVNVTDPY VKIDDLKPFT
MYEFSVKVVK GRRESPWSMV VQNATWENPP NSPPKNLSVV SVEGEGQVLK LQWQPLKLQT
GRVTGYVILY TTNTTKRDRE WSAQAVKGDE NSVIISDLEP NTEYFFKVQA RNSGGNGPFS
ALASFRTGYF SNKLLIYIAI AGVVLAVTLV ITVVIVYYRK RECATSPSRS RSKYQKSCQQ
IKPPDLWIHH DQMELKEKSH CSNDGASSCG AVTLPRSMGA NEFDSRDNHP SNSLDKTTYV
PGYMATAIVT PINTASSSHT SNDSTPSSRT NYPRTQYNIS RAHIAMDQNM DGQMPEHLSG
PVNSRSTCDI GPCNSNYASH PPIAHVPPGS TYAPGMNVTA DPQPVRRIPG LGHPLKSFSV
PAPPPLSAPG TPQPKHIGTP QPSQIIIRPN TSPYKKTMAG CNPTVVGTPA SRITTSNPPP
HTAEEVQPLK PSHSTEELNQ EMANLEGLMI TLNAITASEF EC
//
