ID   A0A1W4X8N0_AGRPL        Unreviewed;       540 AA.
AC   A0A1W4X8N0;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Ras association domain-containing protein 2 {ECO:0000313|RefSeq:XP_018332384.1};
GN   Name=LOC108741907 {ECO:0000313|RefSeq:XP_018332384.1};
OS   Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC   Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX   NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018332384.1};
RN   [1] {ECO:0000313|RefSeq:XP_018332384.1}
RP   IDENTIFICATION.
RC   TISSUE=Entire body {ECO:0000313|RefSeq:XP_018332384.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_018332384.1; XM_018476882.2.
DR   AlphaFoldDB; A0A1W4X8N0; -.
DR   STRING; 224129.A0A1W4X8N0; -.
DR   EnsemblMetazoa; XM_018476882.2; XP_018332384.1; LOC108741907.
DR   GeneID; 108741907; -.
DR   KEGG; apln:108741907; -.
DR   InParanoid; A0A1W4X8N0; -.
DR   OrthoDB; 4211308at2759; -.
DR   Proteomes; UP000192223; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd09401; LIM_TLP_like; 1.
DR   CDD; cd01784; RA_RASSF2_like; 1.
DR   CDD; cd21886; SARAH_RASSF2-like; 1.
DR   Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR033614; RASSF1-6.
DR   InterPro; IPR011524; SARAH_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR001781; Znf_LIM.
DR   PANTHER; PTHR22738:SF15; LD40758P; 1.
DR   PANTHER; PTHR22738; RASSF; 1.
DR   Pfam; PF00412; LIM; 1.
DR   Pfam; PF16517; Nore1-SARAH; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM00132; LIM; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50951; SARAH; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW   ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192223};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT   DOMAIN          2..63
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          389..481
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          489..536
FT                   /note="SARAH"
FT                   /evidence="ECO:0000259|PROSITE:PS50951"
FT   REGION          72..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          188..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          272..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          508..539
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        74..95
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..322
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..343
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..380
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   540 AA;  61163 MW;  E6E83B579288BA04 CRC64;
     MWKCHKCGKP VYFAERKQSL GYDWHPECLR CEECGKRLNP GQHAEHKGVP YCHVPCYGAL
     FGPQLFGHGT RVESHKSFGQ QKTSPKSGNG PSIPRSQIEN KLKIYNNFFD GKSGEIRSRE
     VNNRLILEGS LRIHWGVHGV IHLKEDDDQR TVVTIRKRNS CRANSGSEFD SGDETTCNDI
     SLDSLSKDSS LLTSGDNMTD SMTSDTGIDD INMDTSSSNS ELNLTASVSK DISPKSLTLP
     SKVDTKSVEW DELDDLLQVE RKLDESQKLY QTMPEPLPSS QSSCLDGDLT SDSSPIKING
     NVESSDASDP SWFGSNGHLN RSMSGPDCLE RNRKEKEDLS IEDSTVTDTN PTDEEAVMRR
     PPKTGSTAIK RRPGRRLSRS KIKRRCSING HFYNRETSFF TPPHGSQMSV WVTSLVSTHE
     VINLLLEKYK VESDPTNFAL FIVRDNGEQR RLKEDESPLL VRVLLGPHED VARLFLMDSQ
     NTPEVSNEVA QFLNLSVPEL RAILNQYYSQ EEKEIMKIQD RYKEMKRRIK NRMEELKVRL
//