ID   A0A1W4XE54_AGRPL        Unreviewed;      1078 AA.
AC   A0A1W4XE54;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Chromosome-associated kinesin KIF4A isoform X1 {ECO:0000313|RefSeq:XP_018334299.1};
GN   Name=LOC108743281 {ECO:0000313|RefSeq:XP_018334299.1};
OS   Agrilus planipennis (Emerald ash borer) (Agrilus marcopoli).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Elateriformia;
OC   Buprestoidea; Buprestidae; Agrilinae; Agrilus.
OX   NCBI_TaxID=224129 {ECO:0000313|Proteomes:UP000192223, ECO:0000313|RefSeq:XP_018334299.1};
RN   [1] {ECO:0000313|RefSeq:XP_018334299.1}
RP   IDENTIFICATION.
RC   TISSUE=Entire body {ECO:0000313|RefSeq:XP_018334299.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR   RefSeq; XP_018334299.1; XM_018478797.1.
DR   AlphaFoldDB; A0A1W4XE54; -.
DR   STRING; 224129.A0A1W4XE54; -.
DR   EnsemblMetazoa; XM_018478797.1; XP_018334299.1; LOC108743281.
DR   GeneID; 108743281; -.
DR   KEGG; apln:108743281; -.
DR   InParanoid; A0A1W4XE54; -.
DR   OrthoDB; 602895at2759; -.
DR   Proteomes; UP000192223; Unplaced.
DR   GO; GO:0015630; C:microtubule cytoskeleton; IEA:UniProt.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   CDD; cd01372; KISc_KIF4; 1.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR47969; CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED; 1.
DR   PANTHER; PTHR47969:SF15; ZGC:66125; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000192223}.
FT   DOMAIN          13..336
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS50067"
FT   COILED          378..494
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          560..654
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          758..807
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          855..893
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          921..948
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   BINDING         91..98
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   1078 AA;  124194 MW;  C08897B2E01D05B0 CRC64;
     MNEPNNDRDC NDSVKVAVRI RPLVESEIAR GCNNVLEVIP SLQQVQVADK AFTYNYVYDC
     ESTQEEFYNS CSKKLITNLF KGYNVTILAY GQTGSGKTYT MGTCYDGEGE MGIIPRAIHD
     IFTYVRDNFS YDFTVTVTFM ELYQETLYDL LSKKPKDQCN VEIRDDGKNI LIPNLTEETV
     DSAHKALEFL RIGSLSRVVG STNMNAQSSR SHAIFTINLC MQKKDDSNQN KAAKFHLVDL
     AGSERSKKTG ATGQTFKEGI NINKGLLALG NVISALGDEK LQAGYISYRD SNLTRLLKDS
     LGGNSITLMI ACVSPADYNL EETLSTLRYA DRARKIKNKP IVNQDPKIAE INRLKKTIQQ
     LRLELIGQGG PIVCQGEIDT IRKENDQMKA KIHELTVQLS SSINEKTGLL ERLIILQTSN
     ERLREKLLEI KKEYDTTLNS LNLSIQQNDG DMIRENMRKL EIMKLQLTEL DTEHKKTEEE
     VRMHEADVAQ IQNQMFTNNK ALVNDIEMEK ELKERHEYYA AHQMAKDLQL QELSKMLAMK
     ERLAQQIASN NCYMVDYQAI TETEEKINSL EKEKEDLLVQ LKKAQTTGNE PSAKGAEIRR
     RRIQELEKEI QDLRRKVTEQ ARLIKMKEKD ELKIKQLQNE IQSMKQLKVK LIRDMKQEAD
     KFRQWKKQRE QEVCKLREQD RKRQNQMRVM ETMHSRQQNV LKRKVEEVAA INKRLKDALA
     LRNAVQEQKN SGKVEQTAAW LRQEFNLFVS IIEAKVTLTG LLEDRAALHQ QMENLKADAS
     DEDSEEVKQL KNEIELRSIQ IQDLQQKLLD SDEDNKSRAR FDNIQTMNEA KYCLKMLFQL
     TSEIKKNEVN LEYRMSELVQ SQNEMANKLK VLEANLIKNN QNHQLEMANV QKEYEEKVSV
     LLRQLRGVQV SDTEKEMNYR FNIQQQRIEM LEKQLEEKQK EGETVIVENS KLARTIDDIT
     VEENILDVSV EVEVDNPVAD PDWRKTPLAK RIRKLRKTSP EFSSQTVKRS SEGGCTCKGS
     CATRNCGCKK FQLSCNPNCR CDPLNCVNRN EKKERSESTN GDDFKKPSNL RFGNALLL
//