ID A0A1W5D3M2_9LECA Unreviewed; 479 AA.
AC A0A1W5D3M2;
DT 07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Winged helix-turn-helix DNA-binding domain {ECO:0000313|EMBL:SLM37727.1};
OS Lasallia pustulata.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Lecanoromycetes;
OC OSLEUM clade; Umbilicariomycetidae; Umbilicariales; Umbilicariaceae;
OC Lasallia.
OX NCBI_TaxID=136370 {ECO:0000313|EMBL:SLM37727.1, ECO:0000313|Proteomes:UP000192927};
RN [1] {ECO:0000313|Proteomes:UP000192927}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sharma R., Thines M.;
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; FWEW01001850; SLM37727.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W5D3M2; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000192927; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd20032; FH_FOXO; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45881; CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR45881:SF5; FORK-HEAD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 247..340
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 247..340
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 186..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 52466 MW; 5D554935475C46A8 CRC64;
MSETDLGLHK SSRFQQHQYL KGETGAMPAL TGPALSTVPD VPHVDKVDID FDGNLPMTTI
PPWEDLEISA LSQGSYNYHI GSEYGNSNYQ STSGLVQGKA MVSSLWDDNF PRDSTLAYSP
SPSTCPRSHS QDIQAFRHAM DDNRYSAWPY LLDATNDQSF PTIKRCRESQ NNLLLIPNSS
TSRSLLSDES FQNCTPATSP SPLPSKRSNL RSAISPDVPE GYEGANGLAT ANGDETDPEG
GVISEPYAQL IYRALKSAPE HKMVLKEIYE WFEKNTDKAT DPSSKGWQNS IRHNLSMNGA
FRKVDQPPPT DEAKKGYIWV LDRSALEGGV KSTTRFRKNV PNKKVGKSEH PAPQRQRSGA
KGGKAAKKAA KLRRSARFNE SKGLPYVDRA AVDAKPAFNT RNSGLSAADT VPYHSSGWPY
SIPTPNTTTH SPDLYETSYG YEQIVGCADG LPSEPLFYNA PGHSFCDSID SSDCCGFSC
//
