ID   A0A1W5D7B6_9LECA        Unreviewed;       384 AA.
AC   A0A1W5D7B6;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Saccharopine dehydrogenase / Homospermidine synthase {ECO:0000313|EMBL:SLM38996.1};
OS   Lasallia pustulata.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Lecanoromycetes;
OC   OSLEUM clade; Umbilicariomycetidae; Umbilicariales; Umbilicariaceae;
OC   Lasallia.
OX   NCBI_TaxID=136370 {ECO:0000313|EMBL:SLM38996.1, ECO:0000313|Proteomes:UP000192927};
RN   [1] {ECO:0000313|Proteomes:UP000192927}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sharma R., Thines M.;
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FWEW01003236; SLM38996.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W5D7B6; -.
DR   OrthoDB; 2184985at2759; -.
DR   Proteomes; UP000192927; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR11133:SF25; ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW   Lysine biosynthesis {ECO:0000256|ARBA:ARBA00023154};
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          7..137
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
FT   DOMAIN          141..376
FT                   /note="Saccharopine dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16653"
SQ   SEQUENCE   384 AA;  41635 MW;  D6058A450247AFE2 CRC64;
     MAGSKKVLLL GAGFVTKPTV QILSNADIEV TVGLSKTETP SGSCTDKSAA CRTPENSKNL
     SQGIKNAHPI SLDVTNAAAL DAAVEKVDVV FSSIPYTFHA TVIKSAIRKK KNVVTSYVSP
     AMLELESKVK EAGITVMNEI GLDPGIDHLY AVKTIGQVIT SFLFYCGGLP APEASDNPPG
     YKFSWSSRVV LLALTNTAKY YKDGKIEEVA GPELMGTAKP YFIYPATSGK ESDIEWAISS
     KTKFADNDEK NRIFAGLPWI GMFSEDKITP RGTPLDTLCT TLEQKIQYGS GERDLVMLQH
     KFEIEHKDGR KETRTSTLVD YGDHNGYSSM AKLVGAPCEI AVKQVLDGTI SEKGILAPMS
     PKTNNPLIEE LKKYGIELKE QTLA
//