ID A0A1W6JN57_9CAUD Unreviewed; 704 AA.
AC A0A1W6JN57;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=DNA gyrase/topoisomerase IV subunit A {ECO:0000313|EMBL:ARM67673.1};
GN ORFNames=LW81_103 {ECO:0000313|EMBL:ARM67673.1};
OS Lactococcus phage LW81.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Audreyjarvisvirus; Audreyjarvisvirus LW81.
OX NCBI_TaxID=1965482 {ECO:0000313|EMBL:ARM67673.1, ECO:0000313|Proteomes:UP000224987};
RN [1] {ECO:0000313|EMBL:ARM67673.1, ECO:0000313|Proteomes:UP000224987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28300778;
RA Mahony J., Moscarelli A., Kelleher P., Lugli G.A., Ventura M., Settanni L.,
RA van Sinderen D.;
RT "Phage Biodiversity in Artisanal Cheese Wheys Reflects the Complexity of
RT the Fermentation Process.";
RL Viruses 9:E45-E45(2017).
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrA/ParC subunit
CC family. {ECO:0000256|ARBA:ARBA00008263}.
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DR EMBL; KY554777; ARM67673.1; -; Genomic_DNA.
DR Proteomes; UP000224987; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.1360.40; -; 1.
DR Gene3D; 2.120.10.90; DNA gyrase/topoisomerase IV, subunit A, C-terminal; 1.
DR Gene3D; 3.90.199.10; Topoisomerase II, domain 5; 1.
DR Gene3D; 1.10.268.10; Topoisomerase, domain 3; 1.
DR InterPro; IPR035516; Gyrase/topoIV_suA_C.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR013758; Topo_IIA_A/C_ab.
DR InterPro; IPR013757; Topo_IIA_A_a_sf.
DR InterPro; IPR002205; Topo_IIA_dom_A.
DR PANTHER; PTHR43493:SF5; DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL; 1.
DR PANTHER; PTHR43493; DNA GYRASE/TOPOISOMERASE SUBUNIT A; 1.
DR Pfam; PF00521; DNA_topoisoIV; 1.
DR SMART; SM00434; TOP4c; 1.
DR SUPFAM; SSF101904; GyrA/ParC C-terminal domain-like; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ARM67673.1};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 6..445
FT /note="DNA topoisomerase type IIA"
FT /evidence="ECO:0000259|SMART:SM00434"
SQ SEQUENCE 704 AA; 79041 MW; 8D8212977536F8D9 CRC64;
MEIVEKGLQH IVTDNMGQYS TYVLLSRAIP DFRDGLKPSY RRILWAMHEK KATRFTKSAN
IVGEAMLLHP HGSTYPTMVG MAQKDSQLNP MVIGKGNFGQ HASELAFGAE RYTEVKLSAI
GLDIMADVKK DGVDFVDNYD GTRKIPEVFP VKYPTILAYA QSGIGVGFSS SIPSFNTTEL
CEAIIKRIED NEETLLIPDF GTGAYIINDP DVVKSINENG SGSINQRAKV EFDKDSREII
VKEIPYGTTK EKIIERIIKL NKEDKLKEVT KVEDGSGLKG LEIIITAKRG VDLEQLLEKL
YQITPMQASY STNLMVINRQ GLPEKMGVWS LIAKWLDWRT DTYQRMIMKD IQTKQVQLEI
LYGLENIKDD LEHVIKIIRN STDDNVIQNL SSEFSLTKLQ AERVSGLKLK NLTTTFIKKQ
LSNIKSLEKE IEQLEWTVEK PQRIHKLIVQ DMKDVIAQFG TPRKSQLIDK SVVAKKAKLS
PANTVEEYNV KVIVTKDGYV KKIPLTSLRG NAEIQFKEGD FLTSEIDTDN GEELLIFTNK
QNVYKKQLDD LNDTKPKDLG NYIPSLIDLE EGEEIQGIIT LSKDTKYVLL GFEDGKVAKV
NVEAYRTSTK RSKLKNGVVG KMIVLLTTLT DDVDIMSISA SDKAIVTNTS MISAKNSKAT
QGITNQKLKA GESIKKLLVL KEGEEDNREY YRVQSAGAGK KFKG
//
