ID A0A1W6SKZ2_9PROT Unreviewed; 801 AA.
AC A0A1W6SKZ2;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:ARO86465.1};
GN ORFNames=EBAPG3_000970 {ECO:0000313|EMBL:ARO86465.1};
OS Nitrosospira lacus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosospira.
OX NCBI_TaxID=1288494 {ECO:0000313|EMBL:ARO86465.1, ECO:0000313|Proteomes:UP000012179};
RN [1] {ECO:0000313|EMBL:ARO86465.1, ECO:0000313|Proteomes:UP000012179}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=APG3 {ECO:0000313|EMBL:ARO86465.1,
RC ECO:0000313|Proteomes:UP000012179};
RX PubMed=25336720; DOI=10.1099/ijs.0.070789-0;
RA Urakawa H., Garcia J.C., Nielsen J.L., Le V.Q., Kozlowski J.A., Stein L.Y.,
RA Lim C.K., Pommerening-Roser A., Martens-Habbena W., Stahl D.A., Klotz M.G.;
RT "Nitrosospira lacus sp. nov., a psychrotolerant, ammonia-oxidizing
RT bacterium from sandy lake sediment.";
RL Int. J. Syst. Evol. Microbiol. 65:242-250(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP021106; ARO86465.1; -; Genomic_DNA.
DR RefSeq; WP_004180771.1; NZ_CP021106.3.
DR AlphaFoldDB; A0A1W6SKZ2; -.
DR KEGG; nlc:EBAPG3_000970; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000012179; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000012179};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 550..720
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 801 AA; 88069 MW; BD27C9E55CA2C0AB CRC64;
MRAYILAFAF GVGLLQQQAE LPDLLWAWLL VPGSVGAFLL WRCRVAIFSI TAKILLALIF
LGAGLFWAAA FAQWRLADAL PHEWEGRDIQ LAGVVAELPQ ANENGLRFAF DVEQVLTEGA
IVPRRISLAW YNERRKYAEN SVSVLPRINA GERWRITVRL KRPRGSVNPH GFDFEEWALE
RNIRATGYVR KADDNLRLDA MVNQPSYRVE RLRQEIREHF IQALPDHAYT GVLIALAVGD
QRAILGGQWQ IFTRTGVNHL MSISGLHVTM VSGLIFALVY GLWRRSHRLA LWLPARKAAV
IAGLAAAFGY ALLAGFAVPA QRTVYMLAAI ALALWLGRFA SATAVLAWAL LIVVVLDPWA
VLSPGFWLSF GAMAFIMLVT AGRIGKMHWL SGWARVQWAI TLSLIPLLLA MFQQVSLVSP
FANAIAVPLV SLVVVPLTLL ATLPLLDFML LPAHVVLSGC MEMLRWMSDV PQAVWSQHAP
PAWAVAAGMA GIVWMLLPGG LGLGLRGGPG LATGFPARWL GAVALLPIFL VLPPKPAPGE
LWLTVLDVGQ GLAVVARTEN HALLFDTGPA FSTEADSGNR AIVPFLRGEG IRHLDAMIVT
HADSDHSGGA LSVLEAVPVE WLVSSLHADH PIQLAASNKR QCRAGQSWQW DGVRFDMLHP
TEQSYSNPKR GTNALSCVLK ITTIHGSVLL PADIEKSSEY QLIENDGNAL SSTVLVAPHH
GSKTSSTGEF VRQVNPRLVI FTVGYRNRFG HPREEVMERY RALGSTLLRS DNDGAVLLRF
ADSKVAVETL RALRRRYWQD T
//
