ID   A0A1W6YWD7_9BORD        Unreviewed;       790 AA.
AC   A0A1W6YWD7;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Histidine kinase {ECO:0000313|EMBL:ARP85294.1};
GN   ORFNames=CAL13_02980 {ECO:0000313|EMBL:ARP85294.1};
OS   Bordetella genomosp. 9.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=1416803 {ECO:0000313|EMBL:ARP85294.1, ECO:0000313|Proteomes:UP000194139};
RN   [1] {ECO:0000313|EMBL:ARP85294.1, ECO:0000313|Proteomes:UP000194139}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AU17164 {ECO:0000313|EMBL:ARP85294.1,
RC   ECO:0000313|Proteomes:UP000194139};
RA   Spilker T., LiPuma J.;
RT   "Complete and WGS of Bordetella genogroups.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000256|ARBA:ARBA00009773}.
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DR   EMBL; CP021109; ARP85294.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W6YWD7; -.
DR   Proteomes; UP000194139; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.40; -; 1.
DR   InterPro; IPR002549; AI-2E-like.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   PANTHER; PTHR43102:SF2; GAF DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43102; SLR1143 PROTEIN; 1.
DR   Pfam; PF01594; AI-2E_transport; 1.
DR   Pfam; PF01590; GAF; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|EMBL:ARP85294.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000194139};
KW   Transferase {ECO:0000313|EMBL:ARP85294.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        236..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        297..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          625..763
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|Pfam:PF01590"
FT   REGION          594..615
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          771..790
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   790 AA;  85470 MW;  90EF14E88E9B9235 CRC64;
     MPPRSSIDAD SGPPDGAPPL DSVRFAANLV SAALIIAGLY YGRDVLIPLA FAFLISFALS
     PLVGWLGRLR LPRSLSVILV MAVVAVMLGG LGLLLGTQVR SLGQQLPTYQ STMQAKVEEL
     RSSLKTPGVF DRALDTITSV RKQVESAPPP APDGAQPVVV EPRAASPLDT ARAWLAPALE
     PLATLGIVLV FVFISLYDRG DLRDRALRIF GGNLHRSTDA LEEAGTRIGR YLRMQLLVNL
     SYGVPMALGL WLIGVPGALL WGTVAAVMRF VPYVGPMISA IFPIGLAFAV DPGWHMLLWT
     IGLIVVLELI SNNVVEPLLY GTSTGLSAMS LIAAATFWTV LWGPVGLILS TPLTVCILVI
     GRYLPHLQFF ETLLGAAPAL DTPTRLYQRL IADDADEAID IASGEVRKSS VKDFYHDVGI
     EVLRLASREH LRSATAEHRW RVSNGMERLL DDLREEYPPE VQSRNAMTVV CMGGKWELDN
     LASEMLAHAL LMQGIRAESR RLPAVTARAI DNLALDGAEL VCLSYFTANP AAPARHFCRR
     LRHRWPRLRI VLALWNAPAE LLEHDAHKAL GADEVVTTVN EAVLRIEAMV APAADREEPR
     GEAKDESAAA PALDATGLLD GQTREELDGL AQRAADVFDV GFAVIVVISG DRELVVGQNR
     PLTGALPRDE RDIVTMPRDE AIGRPVVAGD TTLVVPDTER DPRFVDHPAV RLWSVRFFAG
     APLRSKDNGV FGALCVFDRE PRTLDDTAIE VLDSMAQEFA AVIAAALDEP GAAAAQDEPP
     SATLAQRVPE
//