ID A0A1W6Z3S8_9BORD Unreviewed; 770 AA.
AC A0A1W6Z3S8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CAL13_17985 {ECO:0000313|EMBL:ARP87891.1};
OS Bordetella genomosp. 9.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=1416803 {ECO:0000313|EMBL:ARP87891.1, ECO:0000313|Proteomes:UP000194139};
RN [1] {ECO:0000313|EMBL:ARP87891.1, ECO:0000313|Proteomes:UP000194139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AU17164 {ECO:0000313|EMBL:ARP87891.1,
RC ECO:0000313|Proteomes:UP000194139};
RA Spilker T., LiPuma J.;
RT "Complete and WGS of Bordetella genogroups.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP021109; ARP87891.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W6Z3S8; -.
DR Proteomes; UP000194139; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF29; SENSOR HISTIDINE KINASE HIK2; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000194139};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..770
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013297960"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 466..681
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 412..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 82596 MW; 44810C253C45F003 CRC64;
MQVNLKRFAI LAITAITLCA GSASAPSKAS PVVDYPAVDS AAPISLRPYT QVYEDRDGRL
ALADILAIEK SDPHRFRPLK EMRRLGAYSG SAWWLRTEIV NAAKAPHALI LVGGPPNLEQ
VDFYLQQDGQ WRHFPAGTMI PALQKDGATG YPAAQFTAAP GEAVAVWIRI ESASPIRLEP
ALYTPGSFVA ARASDNILGG VLTSSIAALG ICAFILFAAS HRRAFLWFGG ICVTIALSEA
ASRAYIQPVF WSMASGWTYR LETVIHAIGA ALTAMFVYAM GQRAGLPAGH RKVYGVIAAL
LVICIVPTHF LPVAVLSMAT LALTVVMGIC LMTSALGTAR LSRNGAILLA AAAVLLLAHA
AGMSLHLPGA SPWLIPSALP QAGTPPVALF SMLACAVALT LWATHRRKSQ RVAPGNKQLA
AKETGSLERD AAPPHAQVPP ATPAAVAPRD EAGHLATPQQ TLVLGYVGHD LRAPLATISG
YARLLRQTAR PEQESYLDMI ERSINYQFSL IDEILAYAEY DLQPFDISAG DVQLPALLEE
LARFGVSLCN HQGNAFRYIP ATQLPAVVRL DAKRTRQAVL NLLGNAAKFT RDGTVCFEAG
VNQRDDGAEL MLQVTNDGTP IPVEHQAEIF SAFRQLRHRD AGSGLGLFIA DRIVHGMGGS
LRFDSSPKLG NRFAITLPIA VADATPIVTR PIHHVAARDG GTQGIAAPPL AARLALAKLA
REGELSEIQQ WTAETRQHHP QYEAFYRAVD QCVDNFDMEC LQRLALLGIT
//
