ID A0A1W7D183_9ACTN Unreviewed; 796 AA.
AC A0A1W7D183;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Ketoreductase (KR) domain-containing protein {ECO:0000259|Pfam:PF08659};
GN ORFNames=CAG99_19815 {ECO:0000313|EMBL:ARQ70786.1};
OS Streptomyces marincola.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2878388 {ECO:0000313|EMBL:ARQ70786.1, ECO:0000313|Proteomes:UP000194218};
RN [1] {ECO:0000313|EMBL:ARQ70786.1, ECO:0000313|Proteomes:UP000194218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCSIO 03032 {ECO:0000313|EMBL:ARQ70786.1,
RC ECO:0000313|Proteomes:UP000194218};
RA Ma L., Zhu Y., Zhang W., Zhang G., Tian X., Zhang S., Zhang C.;
RT "Complete genome sequence of Streptomyces sp. SCSIO 03032 revealed the
RT diverse biosynthetic pathways for its bioactive secondary metabolites.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP021121; ARQ70786.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W7D183; -.
DR KEGG; smao:CAG99_19815; -.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000194218; Chromosome.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR013968; PKS_KR.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF08659; KR; 1.
DR SMART; SM00822; PKS_KR; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000194218}.
FT DOMAIN 229..448
FT /note="Ketoreductase (KR)"
FT /evidence="ECO:0000259|Pfam:PF08659"
SQ SEQUENCE 796 AA; 84682 MW; 7CADBF2E1A4D6926 CRC64;
MTTATTPAAG GTDVQPVSRM VWRLTGLPPL PDPETDAPER LAGLRVLLIN GDPGTAAAVE
RELKGHGALV HRGAGGAPAD AVVDLAMDPA PAGGQPAGAW HEALTETVTA LRAVYEDWAA
ESDARRLFYL AVTHLGGGMG QHARDEPAQP LGGVWAGLAK TLHREFPNCN ARVVDVDDAA
RADLPAVIAA ELGRTGPIEV GRRGGARLTL TPVEAPVGPP AVPLGPGDTV LISGGARGIG
WRLARELAGR DGAHVVVTGR EPFPTGDEPW WGLDEEGWRA FERETWRLRD PGTPPARVRS
GLARTRRQWE VATHLTTARR EGLAIEYAQC DITDPAQVRD LVRRHGARLA GVIHNAGVDS
AARLPRTTDE EIGRTVRTKI DGFLNLFEEV RRLPLRFFCS VGSLTGRLGG MVGQLGYAAA
NEGLARLGTW AARRADFPVM TLAWPTWDRV GLIANFSAAL RYMPALDVTE GLARWRAELL
AGSRGEVTFV GPLGKAIDPG QATGYPVVPA LPGYAAAFPR IFHLGATTAF TPHARLTTTV
TFERERVPVA GDFQVDGVPA LPLSVLLESA ARGAEWVVPQ DFPTLRLSRI EGVVVPAALL
RFEHSTLRLV REAEGAHEGE EWVVRVRFRR AGEPAGADQE ASVRLVFGDA APAVPAALPD
VPRTTTWRSG SPYLRWRSTV VPLGVWTRDA SGRHVAEVAP CAPGDLWVTP HEVPTVVPVA
PLENLLRLWA GQGGPLSVTS DPLVIGQLAL HADERGPCRI EGDAAVGVWR VTCAHTGEPV
MTVHGPPGPL GGPAPG
//
