ID A0A1W7D2K3_9ACTN Unreviewed; 486 AA.
AC A0A1W7D2K3;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Glutamate synthase {ECO:0000313|EMBL:ARQ71313.1};
GN Name=gltD {ECO:0000313|EMBL:ARQ71313.1};
GN ORFNames=CAG99_23000 {ECO:0000313|EMBL:ARQ71313.1};
OS Streptomyces marincola.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2878388 {ECO:0000313|EMBL:ARQ71313.1, ECO:0000313|Proteomes:UP000194218};
RN [1] {ECO:0000313|EMBL:ARQ71313.1, ECO:0000313|Proteomes:UP000194218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCSIO 03032 {ECO:0000313|EMBL:ARQ71313.1,
RC ECO:0000313|Proteomes:UP000194218};
RA Ma L., Zhu Y., Zhang W., Zhang G., Tian X., Zhang S., Zhang C.;
RT "Complete genome sequence of Streptomyces sp. SCSIO 03032 revealed the
RT diverse biosynthetic pathways for its bioactive secondary metabolites.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
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DR EMBL; CP021121; ARQ71313.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W7D2K3; -.
DR KEGG; smao:CAG99_23000; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000194218; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000194218}.
FT DOMAIN 40..131
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 146..456
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 486 AA; 52441 MW; 6B7D0552321D5305 CRC64;
MADPKGFLTT GREVARTRPV ASRVKDWDEV YVPGSLLPII SKQAGRCMDC GVPFCHNGCP
LGNLIPEWND YAYRGDWAAA SERLHATNNF PEFTGRLCPA PCESACVLGI NQPPVTIKNV
EVTIIDKAWE AGLVTPQPPQ RLSGKTVAVI GSGPAGLAAA QQLTRAGHTV AVYERADRIG
GLLRYGIPEF KMEKRHLNRR IEQMRAEGTK FRTEIEIGRD IEADKLRNRY DAVVIAAGAT
TARDLPVPGR DLNGVHQAME YLPLANKVRE GDLTTAPISA AGKHVVVIGG GDTGADCVGT
AHRQGAASVT QLEIMPRPGD DRPAHQPWPT FPMTYKVTSA HEEGGERVYS VSTTHFEGDE
DGNVAWLHLI EVEFVDGKLT PKPGTEQRIP AQLVTLAMGF TGTDRENGLV GQFGLELDAR
GNIVRDADYA TNVDGVFVAG DAGRGQSLIV WAIAEGRAAA RGVDRYLTGE STLPYPVRPT
DRALAV
//
