ID A0A1W7M928_9SPHN Unreviewed; 549 AA.
AC A0A1W7M928;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=NMD1_01389 {ECO:0000313|EMBL:GAO54293.1};
OS Novosphingobium sp. MD-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1630648 {ECO:0000313|EMBL:GAO54293.1, ECO:0000313|Proteomes:UP000266860};
RN [1] {ECO:0000313|EMBL:GAO54293.1, ECO:0000313|Proteomes:UP000266860}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-1 {ECO:0000313|EMBL:GAO54293.1,
RC ECO:0000313|Proteomes:UP000266860};
RA Okano K.;
RT "Draft Genome Sequence of the microcystin-degrading bacterium
RT Novosphingobium sp. MD-1.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO54293.1}.
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DR EMBL; BBXA01000021; GAO54293.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W7M928; -.
DR OrthoDB; 9767858at2; -.
DR Proteomes; UP000266860; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:GAO54293.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000266860}.
FT DOMAIN 317..447
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 549 AA; 60629 MW; 013F27E3512F55E0 CRC64;
MERFAALLDA LVFTRSRNAK LALIARYLRE TPDPDRGWAL AALTDGLDFP AVKAGTIRAL
MAERVDPVLW TLSRDYVGDT AEAASLLWPA PDHSAPDHSG PDHDVMPAPG VSEAVEILRA
TSRSTAPAAL AGLLDRLDAN GRYALLKLAT GAMRIGISAR LAKVAFADAF GVPVDLVEEY
WHGQEPPYRP LFAWAADGAP PPRTDDRPLF RPFMLAHPLE DGVAIDLESF AAEWKWDGIR
VQIVHAATDQ GGETRVYSRG GDDISSTFPE VAGALGEPAV LDGELLVRGA HQGGETGGAA
SFNALQQRLG RKTVSKRMLE DFPAFVRLYD ALVIGGEDLR DLPWTDRRAR LEAFLPRLDP
ARFDISTLIA VRDFAELADV RARAREDAIE GVMLKRRDSP YVAGRRTGLW YKWKRDPLRI
DCVLMYAQRG SGKRSSFYSD FTFGCWDGDP DAGADLLPVG KAYFGFTDAE LKWLDSHVRQ
HTVNRFGPVR ETDRSLVLEV AFDSVHASKR HKSGVAMRFP RISRIRADKP AHEADRLDTL
KAMIVDPVR
//
