ID A0A1W7MB12_9SPHN Unreviewed; 842 AA.
AC A0A1W7MB12;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Thioredoxin reductase {ECO:0000313|EMBL:GAO54429.1};
DE EC=1.8.1.9 {ECO:0000313|EMBL:GAO54429.1};
GN ORFNames=NMD1_01526 {ECO:0000313|EMBL:GAO54429.1};
OS Novosphingobium sp. MD-1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=1630648 {ECO:0000313|EMBL:GAO54429.1, ECO:0000313|Proteomes:UP000266860};
RN [1] {ECO:0000313|EMBL:GAO54429.1, ECO:0000313|Proteomes:UP000266860}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-1 {ECO:0000313|EMBL:GAO54429.1,
RC ECO:0000313|Proteomes:UP000266860};
RA Okano K.;
RT "Draft Genome Sequence of the microcystin-degrading bacterium
RT Novosphingobium sp. MD-1.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO54429.1}.
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DR EMBL; BBXA01000022; GAO54429.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W7MB12; -.
DR Proteomes; UP000266860; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004791; F:thioredoxin-disulfide reductase (NADP) activity; IEA:UniProtKB-EC.
DR CDD; cd00038; CAP_ED; 2.
DR CDD; cd16367; DMSOR_beta_like; 1.
DR Gene3D; 3.30.70.20; -; 2.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR42859:SF10; ELECTRON TRANSPORT PROTEIN HYDN-RELATED; 1.
DR PANTHER; PTHR42859; OXIDOREDUCTASE; 1.
DR Pfam; PF00027; cNMP_binding; 2.
DR Pfam; PF13247; Fer4_11; 1.
DR Pfam; PF13738; Pyr_redox_3; 1.
DR SMART; SM00100; cNMP; 2.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 4.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:GAO54429.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000266860}.
FT DOMAIN 373..473
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 497..616
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 654..686
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 691..722
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 723..751
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 796..829
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 842 AA; 91413 MW; B61CBEB134123A73 CRC64;
MSAASRAAQL GLSHVLLEKS GHLSDTIYKY QKGKHVMATP SQLILRSDQE FDAGKKEDIL
DKWNRRTAEL GVNVKYNADV KAIRGTGEAI PGSVQQIVSR ARDGSTTTAE LQRHAPPYAI
ELTSGETVLA ENVVLAIGTQ GNPNLLRCPG ADLPHVTYQL DDPYAILDEH VVVIGTGDAG
IENARGLVED AAQGNVVTVL NRAPKSTNVR ESFPTAKEPN AKALVEDDAA GRLTIRYETE
TKAVEPGWIT LSTRDGEEKI RCDRIIARIG SAPPRAFVEG CGIAFASADR LAFPTLSPQF
ESTAPGIFVI GALAGYPLIK HCMNQGYDVI EFINGNTTLK PADEPLLEAR FRDLPGNRSV
TEWLEFLRTR ITILEGMTTL QLREFMLDSD ARAYRKGEVI FEKNDPGSSL FAIASGSVHV
RIDPNDPSRV VPIPAGTIFG EVGLISGRRR GATIVAAEDT ICVEISRNAA LKLQSQVPTA
RRAIERISTE RQILQMFGSG LTPDDIREVV ETARIEQVPA GKPIISEGDE DRDVFVIRVG
SMIVEKEVGG KPVFLSYLPA GSYVGEMALI DGGQRTATVR AAIKSEVIRI DGDAFARVLA
AKPTLLERAR KDMEGRRKTN AFIESRKDSF SGVVDLYSEQ AKFLVSQGLG EATDVLLIDE
TLCVGCDNCE KACADSHDGL SRLDREAGRS FAHLHVPTSC RHCEHPHCMA DCPPNAIQRG
PDGEVSINDT CIGCGNCQRN CPYGVIRMEK VPPKKPSLWS WLFFGSGPGP GEPSYKWSKK
HTKYTGDPAV DELLDRKKAI KCDMCAGIDG GPSCVRACPT GAAIRVSPDE FLTVARLENE
EA
//
