ID   A0A1W9H3F4_9PROT        Unreviewed;       467 AA.
AC   A0A1W9H3F4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Peptidase M16 {ECO:0000313|EMBL:OQW41913.1};
GN   ORFNames=A4S08_11925 {ECO:0000313|EMBL:OQW41913.1};
OS   Proteobacteria bacterium SG_bin4.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=1827381 {ECO:0000313|EMBL:OQW41913.1, ECO:0000313|Proteomes:UP000192864};
RN   [1] {ECO:0000313|EMBL:OQW41913.1, ECO:0000313|Proteomes:UP000192864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SG_bin4 {ECO:0000313|EMBL:OQW41913.1};
RX   PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA   Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT   "Comammox in drinking water systems.";
RL   Water Res. 116:332-341(2017).
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQW41913.1}.
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DR   EMBL; LWDH01000019; OQW41913.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W9H3F4; -.
DR   STRING; 1827381.A4S08_11925; -.
DR   Proteomes; UP000192864; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          47..190
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          199..383
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   467 AA;  52652 MW;  22D87E54F6D48977 CRC64;
     MNSDNRNSFF SVFSIYNFLL IISLTITSSA LANPHEFLLD NGLKLIVKQD HRSPVVVTQV
     WYKVGSIDEV NGVTGVAHVL EHMMFKGTEK VPNGEFSKKI AAAGGRENAF TSYDYTGYYQ
     QLHKKHLPMA MELESDRMHN LLITKEEFEK EIKVVMEERR LRTDDQPRSL LYEKMMSVAY
     QAHPYKNPII GWMNDLENMT IEDVQDWYDR WYAPNNAVLV VVGDVDAEEV HQLAKKYYGA
     IESRPLFSFN ERKPQSEPPQ LGSKRITVKA PAELPYLIMG YHAPAIKNTQ EDWEPYALEI
     LEGVLDGNAS ARLNKSLVRE SQIASSASAG YGAMARGPSF FFLSAVPSAG KTVAELEQAL
     RGEIEKIAKN GITSEELSRV KAQVIAGHVY QRDSIFSQAM QIGRLESIGL SYRDTDLILE
     KLKTVTAEQV RDVARKYFND DSLTVAVLDP QPLEQKTPSR APVGLRH
//