ID A0A1W9H8W3_9PROT Unreviewed; 692 AA.
AC A0A1W9H8W3;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=A4S16_05080 {ECO:0000313|EMBL:OQW43860.1};
OS Proteobacteria bacterium SG_bin6.
OC Bacteria; Pseudomonadota.
OX NCBI_TaxID=1827383 {ECO:0000313|EMBL:OQW43860.1, ECO:0000313|Proteomes:UP000192863};
RN [1] {ECO:0000313|EMBL:OQW43860.1, ECO:0000313|Proteomes:UP000192863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG_bin6 {ECO:0000313|EMBL:OQW43860.1};
RX PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT "Comammox in drinking water systems.";
RL Water Res. 116:332-341(2017).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQW43860.1}.
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DR EMBL; LWDJ01000050; OQW43860.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W9H8W3; -.
DR Proteomes; UP000192863; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:OQW43860.1};
KW Cilium {ECO:0000313|EMBL:OQW43860.1};
KW Flagellum {ECO:0000313|EMBL:OQW43860.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 40..59
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 111..134
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 203..224
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 236..263
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 284..306
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 692 AA; 72739 MW; 40E5B0BE3AF07834 CRC64;
MAGLALPRPA AWARGAALPV AILLLVLLMV VPIPAAMLDL FFVMNITISL AVLMVSLNTQ
KPLDFSAFPS VLLFATLFRL ALNVASTRVV LVHGHEGESA AGHVIEAFGT FLIGGDYVVG
LFVFAILVII NMIVVTKGAG RVSEVSARFT LDALPGKQMA IDADLNAGLI TPEEAKARRI
EVGTEADFYG SMDGSSKFVK GDAIAGLLIL AANVIGGLIL GPLSHGLTIQ DAAQKYVLLA
IGDALVAQLP SLMLSIAAAT IVTRVSSSMD LAGQIGSQFG SAKTWTPVAA ILTLLGVLPG
MPHLVILPAA AGCGYLAYAA HKAAQRPKPL PEAPAAPPAD PSRISWEEVA DTIQVNLDIG
YGLVPLVDER RGAPLMGRIT GVRRQLSKEL GFVVPQVRVR DDINLGPYSY RIIVGGVVLG
EDLASPDEML ALNTGQAYGE LRGKPAKDPT FGLDATWISP GDADAATGMG YLVVDASTVI
ATHLNNLLSA NAAELLGPDE VQSLLDGLKE RAANLVASLS PNPVPLTTLT TVLKGLLSEG
ISLKEFRRIA SAIAVNAQRS LDPEELGELI RPELGALIIQ KLAGVRDPLR VMTLEGQLEG
LLAQAVRSDP ARRHVIDPDL GRRILEALQR AAQPLIAEGK PFALVVQPVI RLAIRKLVKT
AMPDTPVMSF FEVPEDKAVE VVAVIGAPGA LQ
//
