ID   A0A1W9H9N3_9PROT        Unreviewed;       845 AA.
AC   A0A1W9H9N3;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN   ORFNames=A4S16_04585 {ECO:0000313|EMBL:OQW44126.1};
OS   Proteobacteria bacterium SG_bin6.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=1827383 {ECO:0000313|EMBL:OQW44126.1, ECO:0000313|Proteomes:UP000192863};
RN   [1] {ECO:0000313|EMBL:OQW44126.1, ECO:0000313|Proteomes:UP000192863}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SG_bin6 {ECO:0000313|EMBL:OQW44126.1};
RX   PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA   Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT   "Comammox in drinking water systems.";
RL   Water Res. 116:332-341(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQW44126.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LWDJ01000049; OQW44126.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W9H9N3; -.
DR   Proteomes; UP000192863; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR010225; HrpB.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013689; RNA_helicase_ATP-dep_HrpB_C.
DR   NCBIfam; TIGR01970; DEAH_box_HrpB; 1.
DR   PANTHER; PTHR43519; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR   PANTHER; PTHR43519:SF1; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF08482; HrpB_C; 1.
DR   PIRSF; PIRSF005496; ATP_hel_hrpB; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:OQW44126.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          12..175
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          201..363
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          483..510
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          816..845
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   845 AA;  89463 MW;  ACAB2DC5F7F2793C CRC64;
     MLPIHAVLPD LLSALRDQSR AVLVAPPGAG KTTAVAPALL GEPWCTGEIL LLSPRRIAAR
     AAAERMAALA GEKPGETFGH ATRLDTRRSA RTRVTVMTEG IFVARVQADP ELAGVSAVLF
     DEVHERSLDS DLGLALALDA QAAFRPDLRL LAMSATLDGA RFAALMGGAP VIESEGRSFP
     LELRYLGRDP AERIEDAVAR AVRTALLEGE GGVLAFLPGV AEIERTAERL AGLPVALHRL
     HGTLPPAEQR AAIAPEPRGA RKLVLATSIA ETSLTLDGIR IVVDSGLARR PRYDRAAGMT
     RLVTERVSQA AATQRAGRAA RQGPGIAYRL WEEAATAGLP RFDPPEILEA DLSALVLDCA
     RWGVTDPRAL SWLDPPPEAG VLEARGRLRA LGAIDADGRV TPHGEAVAKL PLPPRLAHML
     IEGARQGLGR VAAEVAVLLS ERGLGGNDPD LETRHSRWRR ERGAKAEAAR GLAARWAQIV
     DTNSPRPFRG DAAEERSQTA PSPKPSPLKG RGFLEDIPDP LARCIALAFP DRVARRRDAG
     GEHWASVGGR GFKLDPASSL ARAEWLAVAE TQGMAAGARI LAAAPLDPAS IEALFGDRIE
     THRTARFEPA TGAVQPLRER RLGAIRLASG QDDGAAPEAI AAALLEGVRE NGLALLPWSE
     SALALRARAA FAALHGGPPA LDDAALIERL DDWLPPLLAG KRRLDAIAPE ALTDALKGLL
     GWDGMRALDT LAPARLETPA GSSHAIDYAA EAGPTVECRP QALFGLGAHP MVARGAVPLV
     LSLTSPASRP IQTTRDLPGF WAGSWAAVAK EMRGRYPKHP WPDDPASARA TLKTKNADAR
     AAGLR
//