ID A0A1W9HHM5_9PROT Unreviewed; 694 AA.
AC A0A1W9HHM5;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:OQW47008.1};
GN ORFNames=A4S16_09275 {ECO:0000313|EMBL:OQW47008.1};
OS Proteobacteria bacterium SG_bin6.
OC Bacteria; Pseudomonadota.
OX NCBI_TaxID=1827383 {ECO:0000313|EMBL:OQW47008.1, ECO:0000313|Proteomes:UP000192863};
RN [1] {ECO:0000313|EMBL:OQW47008.1, ECO:0000313|Proteomes:UP000192863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG_bin6 {ECO:0000313|EMBL:OQW47008.1};
RX PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT "Comammox in drinking water systems.";
RL Water Res. 116:332-341(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQW47008.1}.
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DR EMBL; LWDJ01000014; OQW47008.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W9HHM5; -.
DR Proteomes; UP000192863; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 64..236
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 268..584
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 649..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 694 AA; 74894 MW; 1D6B8519E38F9994 CRC64;
MNPPSRIVTE AHQTFSFNRR TVALGIGQIG VGVVLGARMG WLSIAENARY NMLAESNRVN
LTLIPPRRGW LIDRNGAPIA NNRTDFRVDI IPDRLDDKDR VLGLLQNILA LPPEEMERIR
LDLKHSAGFQ PVQVADDLDW ERFAAVSVRL PELPGVAPTR GYSRNYPAGA AVAHLTGYVG
AASAEQYRAT RDPLLVTPGF KIGKDGIEKQ LDSRLRGSPG AKRVEVTAHG RLVRELAQRP
DAPGQTVRLT IDAGLQEYAA RRLGTNSGSC VVMDCLTGEV LAFVSMPAYD PNSFSDGISH
FEWEMLSKND HVPLMNKALQ GLYPPGSTVK PMNALALLHA GVSPNDRVVC SGALRVGSGV
FHCHKRRGHG AIDMHNAVAQ SCDIYFYEMS RRLGYDRFAP TLRMLGMGQK FDLPFASQRY
GTVPDSAWKQ KKYKESWTVA DSLNASIGQG YVLANPMQLA VAAARLGSGL EVHPRLFVDP
KAPPPRAMPI DPDHFKTIHA AMHAVVNGGG TAGAARLNLP GIELAAKTGT AQVRRITMAE
RARGVLSNGQ LPFKLRDHAL FIAFAPSDKP RYALGMVLEH NGHVNRVLDT PLTARDIMTW
LFDRQRAEAS LAEIEASWGG DIKTRMAAEA TAYRAALAAE ANPAQQQATE LDAAAATESE
AVDAASDASN AAAAALGNSA SGGVAAEGSR EQPD
//
