ID   A0A1W9HI81_9PROT        Unreviewed;       310 AA.
AC   A0A1W9HI81;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   03-MAY-2023, entry version 13.
DE   SubName: Full=Acetoin dehydrogenase {ECO:0000313|EMBL:OQW46947.1};
GN   ORFNames=A4S09_02445 {ECO:0000313|EMBL:OQW46947.1};
OS   Proteobacteria bacterium SG_bin7.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=1827384 {ECO:0000313|EMBL:OQW46947.1, ECO:0000313|Proteomes:UP000192385};
RN   [1] {ECO:0000313|EMBL:OQW46947.1, ECO:0000313|Proteomes:UP000192385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SG_bin7 {ECO:0000313|EMBL:OQW46947.1};
RX   PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA   Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT   "Comammox in drinking water systems.";
RL   Water Res. 116:332-341(2017).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQW46947.1}.
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DR   EMBL; LWDK01000055; OQW46947.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W9HI81; -.
DR   STRING; 1827384.A4S09_02445; -.
DR   Proteomes; UP000192385; Unassembled WGS sequence.
DR   GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR   CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR029061; THDP-binding.
DR   PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR   PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          1..301
FT                   /note="Dehydrogenase E1 component"
FT                   /evidence="ECO:0000259|Pfam:PF00676"
SQ   SEQUENCE   310 AA;  34243 MW;  C68CF7663FF7ABC2 CRC64;
     MKRIRHVEET IAAKYHEQKM RCPVHLSTGQ EAVSAAVGLA LRKTDFAVSG HRAHAHYIAK
     GGSVPKMLAE IYGKETGCCA GKGGSMHLID QSVGFMGSTA IVGGTIPVGV GLALSSKLKG
     EDKVTCVFVG DGAIEEGAFY ESANFAALKK LPVLFLCENN FYSVYSHLRV RQPSERSIQK
     MVEGIGIPGF SGDGNNVIEV YHQTLKALKE IRAGNGPRFL EFTTYRWREH CGPNFDNNIG
     YRTEEEYLHW RAKEPIGAFE AVMVNEGHLS ESEVKEMERQ INIEVDEAFH FAETSPFPKP
     EAAYTHLFSE
//