ID A0A1W9HSK1_9PROT Unreviewed; 698 AA.
AC A0A1W9HSK1;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:OQW50217.1};
GN ORFNames=A4S09_00020 {ECO:0000313|EMBL:OQW50217.1};
OS Proteobacteria bacterium SG_bin7.
OC Bacteria; Pseudomonadota.
OX NCBI_TaxID=1827384 {ECO:0000313|EMBL:OQW50217.1, ECO:0000313|Proteomes:UP000192385};
RN [1] {ECO:0000313|EMBL:OQW50217.1, ECO:0000313|Proteomes:UP000192385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG_bin7 {ECO:0000313|EMBL:OQW50217.1};
RX PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT "Comammox in drinking water systems.";
RL Water Res. 116:332-341(2017).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQW50217.1}.
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DR EMBL; LWDK01000030; OQW50217.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W9HSK1; -.
DR STRING; 1827384.A4S09_00020; -.
DR Proteomes; UP000192385; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 115..138
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 207..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 239..262
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 698 AA; 75989 MW; 1EC0EDA34A809C05 CRC64;
MEDLFQFLKK FEKFTKNTDL LMAVGLIGVL AVMIIPLPPA LLDMSLTLSL ALSILVLLVA
LYINKSLDFS VFPSLLLITT LLRLSLNVAS TRLILAHGHE GPQAVGEVIS AFGNFVVGNN
YVIGFIVFVI LVIINFIVIT KGSGRIAEVA ARFTLDAMPG KQMSIDADLN AGLITEEDAR
RRRKEIEEEA DFYGAMDGAS KFVRGDAIAG IIITLVNVIG GLLIGTIQKG LDLSTAAKYY
TMLTIGDGLV TQIPALIIST AAGMVVTRNA SATNVSSEVA RQLLVNPKAV GITGGVLFTL
GLVPGLPTLP FFTMAIFLTG LSWIIKRYQK DDIEQKKREA EEASLKPTQE KVESLLPLDV
IELEVGYALI NAVESDQSGD LVERIVSIRK QFATDLGIVV PSVHIRDNLQ LDPGDYRILI
KGNKVASGKL KSDCYMAMDP GNVTQKISGI PTTEPAFGLD ALWVSKNQKE QAEMAGYTVV
DIPTIMATHL TEVVRSHACE LLGRQEVQAL IDNFKKNYPK VVEELIPEVL NLGGVVKVLQ
NLLKEGVSIR DLLTIFETLA DEAPKTKDLD LLTESVRRNL NRSITAKFVN DRGNVSVISM
SPRIENLITN SLIQTEQGVQ LVMDPVIAQR LISEISKTIE SNPEVAAVPV VLTTPTNRRH
LYKLTSRFIP QLSVISHSEV SSDARVKSVG IVELENAS
//
