ID   A0A1W9I3R4_9PROT        Unreviewed;       333 AA.
AC   A0A1W9I3R4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=NADP-dependent oxidoreductase {ECO:0000313|EMBL:OQW54346.1};
GN   ORFNames=A4S14_15335 {ECO:0000313|EMBL:OQW54346.1};
OS   Proteobacteria bacterium SG_bin9.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=1827385 {ECO:0000313|EMBL:OQW54346.1, ECO:0000313|Proteomes:UP000192684};
RN   [1] {ECO:0000313|EMBL:OQW54346.1, ECO:0000313|Proteomes:UP000192684}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SG_bin9 {ECO:0000313|EMBL:OQW54346.1};
RX   PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA   Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT   "Comammox in drinking water systems.";
RL   Water Res. 116:332-341(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQW54346.1}.
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DR   EMBL; LWDM01000073; OQW54346.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W9I3R4; -.
DR   STRING; 1827385.A4S14_15335; -.
DR   Proteomes; UP000192684; Unassembled WGS sequence.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd05288; PGDH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR041694; ADH_N_2.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR045010; MDR_fam.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR   PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR   Pfam; PF16884; ADH_N_2; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          17..331
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   333 AA;  35204 MW;  900A854F0F1A5389 CRC64;
     MSASVNRQVL LAEKPSGKLS PSHFKLVDGK VPEPKDGEVL LRTRLISLDA ANRAWMQGAT
     YRAAVEANTV MAGGSISEVV SSKAPGFTTG DLIFADTGWQ DYAALPAKHL IKVPKIEPMS
     YLLSVYGIAG LTAYFGLLNV GQPKEGNTVV VSAAAGSVGS IVGQIAKIKG CRTVGIAGGA
     EKCKWLTSEL GFDAAVDYKN TALFKELKAA APNGIDVYFD NVGGDIFETC LFQMNNRGRI
     ACCGAVSQYD GAPSATGPRG VPGLIVVKRL VVQGFIVTDF NAERDKALAD LQSWVASGKL
     KVQEDIINGI ENTPQALIGL LNGENRGKRM VRV
//