ID   A0A1W9IIC4_9PROT        Unreviewed;       246 AA.
AC   A0A1W9IIC4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Histidine utilization repressor {ECO:0000313|EMBL:OQW59408.1};
GN   ORFNames=A4S14_05425 {ECO:0000313|EMBL:OQW59408.1};
OS   Proteobacteria bacterium SG_bin9.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=1827385 {ECO:0000313|EMBL:OQW59408.1, ECO:0000313|Proteomes:UP000192684};
RN   [1] {ECO:0000313|EMBL:OQW59408.1, ECO:0000313|Proteomes:UP000192684}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SG_bin9 {ECO:0000313|EMBL:OQW59408.1};
RX   PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA   Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT   "Comammox in drinking water systems.";
RL   Water Res. 116:332-341(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQW59408.1}.
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DR   EMBL; LWDM01000023; OQW59408.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W9IIC4; -.
DR   STRING; 1827385.A4S14_05425; -.
DR   Proteomes; UP000192684; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006547; P:histidine metabolic process; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 3.40.1410.10; Chorismate lyase-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR028978; Chorismate_lyase_/UTRA_dom_sf.
DR   InterPro; IPR010248; His_ut_repres.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR011663; UTRA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR02018; his_ut_repres; 1.
DR   PANTHER; PTHR44846:SF16; HISTIDINE UTILIZATION REPRESSOR; 1.
DR   PANTHER; PTHR44846; MANNOSYL-D-GLYCERATE TRANSPORT/METABOLISM SYSTEM REPRESSOR MNGR-RELATED; 1.
DR   Pfam; PF00392; GntR; 1.
DR   Pfam; PF07702; UTRA; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SMART; SM00866; UTRA; 1.
DR   SUPFAM; SSF64288; Chorismate lyase-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
FT   DOMAIN          12..80
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   246 AA;  27874 MW;  6221AE7CE601FC34 CRC64;
     MTLVSTPRSG APTLYKRIRT DIEKRILSGK WPPGHRIPSE HELMKRYDCS RMTVNKALTE
     LAQADLIQRR KRAGSFVHRP QVLSAVLEIA DIRAEITALG RRYDYRLLVR RRRAASRADR
     SWLGVEQPCD VLALEAYHSA DGIPFAMETR LINLDAVPEA RQADFTRESP GTWLLTHVPW
     SEAEHRIAAI GADDKIAKTL HTAEGSPCLV INRRTWRNGQ TLTAVRLVYP GQEHQLVARF
     KGRQAA
//