ID   A0A1W9JAR9_9PROT        Unreviewed;       276 AA.
AC   A0A1W9JAR9;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Lipopolysaccharide core heptose(I) kinase {ECO:0000256|PIRNR:PIRNR037318};
DE            EC=2.7.1.- {ECO:0000256|PIRNR:PIRNR037318};
GN   ORFNames=BVN34_05785 {ECO:0000313|EMBL:OQW69025.1};
OS   Proteobacteria bacterium ST_bin12.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=1978760 {ECO:0000313|EMBL:OQW69025.1, ECO:0000313|Proteomes:UP000192616};
RN   [1] {ECO:0000313|EMBL:OQW69025.1, ECO:0000313|Proteomes:UP000192616}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ST_bin12 {ECO:0000313|EMBL:OQW69025.1};
RX   PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA   Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT   "Comammox in drinking water systems.";
RL   Water Res. 116:332-341(2017).
CC   -!- FUNCTION: Kinase involved in the biosynthesis of the core
CC       oligosaccharide region of lipopolysaccharide (LPS). Catalyzes the
CC       phosphorylation of heptose I (HepI), the first heptose added to the
CC       Kdo2-lipid A module. {ECO:0000256|PIRNR:PIRNR037318}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS core biosynthesis.
CC       {ECO:0000256|PIRNR:PIRNR037318}.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. KdkA/rfaP
CC       family. {ECO:0000256|PIRNR:PIRNR037318}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQW69025.1}.
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DR   EMBL; MSXP01000005; OQW69025.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W9JAR9; -.
DR   STRING; 1978760.BVN34_05785; -.
DR   UniPathway; UPA00958; -.
DR   Proteomes; UP000192616; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR017172; Lsacc_core_hep_kinase_RfaP.
DR   Pfam; PF06293; Kdo; 1.
DR   PIRSF; PIRSF037318; RfaP; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PIRNR:PIRNR037318};
KW   Kinase {ECO:0000256|PIRNR:PIRNR037318, ECO:0000313|EMBL:OQW69025.1};
KW   Lipopolysaccharide biosynthesis {ECO:0000256|PIRNR:PIRNR037318};
KW   Nucleotide-binding {ECO:0000256|PIRNR:PIRNR037318};
KW   Transferase {ECO:0000256|PIRNR:PIRNR037318}.
SQ   SEQUENCE   276 AA;  31794 MW;  FFB5C234D8EC1E2C CRC64;
     MIFKQILEVP AVIKQYINKP DVFNALLRMQ GKTFRDVKGR KTIQVRLYSE NGVVQSYFIK
     QHFGVGWREI IKNLTAIKWP ILGAMTEVKA IQKLNALNIA TTPLVAYGQR GHNPATLQSF
     VLTADLGDIT SLEDLTMDWP ANPPDAIFKR KLIIAVAKIA KKLHENGINH RDFYIGHFCL
     DNLSKPEIKL YLIDLHRVLI HAKPSINGNM KDIAALYFSS MDIGLTKRDL MCFKKHYSKM
     DKQFWQQVES RATKLYAKFH SQKFQQRLKK EKSAIH
//