ID   A0A1W9K861_9PROT        Unreviewed;       356 AA.
AC   A0A1W9K861;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE            EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN   ORFNames=BVN32_01840 {ECO:0000313|EMBL:OQW80084.1};
OS   Proteobacteria bacterium ST_bin14.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=1978762 {ECO:0000313|EMBL:OQW80084.1, ECO:0000313|Proteomes:UP000192961};
RN   [1] {ECO:0000313|EMBL:OQW80084.1, ECO:0000313|Proteomes:UP000192961}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ST_bin14 {ECO:0000313|EMBL:OQW80084.1};
RX   PubMed=28390307; DOI=10.1016/j.watres.2017.03.042;
RA   Wang Y., Ma L., Mao Y., Jiang X., Xia Y., Yu K., Li B., Zhang T.;
RT   "Comammox in drinking water systems.";
RL   Water Res. 116:332-341(2017).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC         methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC         ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00001709};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQW80084.1}.
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DR   EMBL; MSXR01000003; OQW80084.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W9K861; -.
DR   STRING; 1978762.BVN32_01840; -.
DR   Proteomes; UP000192961; Unassembled WGS sequence.
DR   GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR   CDD; cd06558; crotonase-like; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR045004; ECH_dom.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   InterPro; IPR032259; HIBYL-CoA-H.
DR   PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR   Pfam; PF16113; ECH_2; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          14..343
FT                   /note="Enoyl-CoA hydratase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF16113"
SQ   SEQUENCE   356 AA;  38507 MW;  DF33355E9772D82F CRC64;
     MTNDVIADVQ GRTGRIRLNR PAAIHALNTP MCAAMLAALE SWRVDTRVEA VLIDHAPSPD
     DDPKKSRGFC AGGDIRMLAT SGAADGVEAR QFFHTEYQMN HKLFTYVKPV IAFMDGITMG
     GGVGISLPCQ YRVATENTRL AMPETGIGLF PDVGGGWYLS RLPGRMGQFL ALTGHRLDGA
     ECLALGLATH YLPAAALDAA KARIVADPSA IEAILADLSV APPAAKILVH QPAIDRLFAA
     DTLETVFAAL AADPSDWARA QSALLSSKSP QTMKVSLRLL HEGAQMRDFA AEMRQEYAVG
     CRVVQRHDFI EGVRAVIIDK DNAPRWNPAT PEEVSDHLIN QIFAPLPDDE AWTPHN
//