ID   A0A1W9P4G9_9BACT        Unreviewed;       575 AA.
AC   A0A1W9P4G9;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Penicillin-binding protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=B5M53_07105 {ECO:0000313|EMBL:OQX53297.1};
OS   Candidatus Cloacimonas sp. 4484_209.
OC   Bacteria; Candidatus Cloacimonadota; Candidatus Cloacimonadia;
OC   Candidatus Cloacimonadales; Candidatus Cloacimonadaceae; Cloacimonas.
OX   NCBI_TaxID=1968525 {ECO:0000313|EMBL:OQX53297.1, ECO:0000313|Proteomes:UP000192614};
RN   [1] {ECO:0000313|Proteomes:UP000192614}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Dombrowski N., Seitz K., Teske A., Baker B.;
RT   "Novel pathways for hydrocarbon cycling and metabolic interdependencies in
RT   hydrothermal sediment communities.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OQX53297.1}.
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DR   EMBL; MZGI01000123; OQX53297.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W9P4G9; -.
DR   Proteomes; UP000192614; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          51..189
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          236..542
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   575 AA;  63818 MW;  8260AD90E226A6C4 CRC64;
     MRGETVKINI VVFLLVGIWS FFFLRLGYIQ IFRRGYYTEK SNRQSVKKVV VYPERGKIFD
     RYGKEIATNV ESKTIIAFPG EVRDKKRAAL LLAKHGFGSF KGLYKEMQKK KFMYIKRNID
     EDPPEDIRKI KGIELLMNKK RFYPYGKSFS SVIGFVGTDY TGLEGLEFAF DSLLSGKPGW
     AVLQKAPNGV LFPHPALPRK SPQSGKNLVL TVDADLQSIV FSELKNVIER TSSKGGVVIV
     INPKTGEILA MVSLPGFDPN HPLKSDRNTW VNRAISELFE PGSTFKIVAA TAAVENKLYN
     LDDIVEDGEG IIRIGRVKIS DAEKHGPLTF VQFVEHSSNV AAIKIAERIG KKRFYCYARS
     FGFGSRTKIG LPGEEKGYLG SPLHWSPLKF ATMSFGQGVS ATALQLVFAY AAVANDGILL
     KPLLVKSIVS NDGDTLFNAS PVIVRRVMHK ETAQILKQIL EGVVNFGTGK YARVDGLEIA
     GKTGTAQKSN PELGYKKGGY VASFIGFFPV YDPQFLIGVF IDEPKGLHWG GYVAAPLFKK
     IVQRILCLDN YNSKIPRLLV EQSKGTEANE TIKSN
//