ID A0A1W9P7B1_9BACT Unreviewed; 1093 AA.
AC A0A1W9P7B1;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Tricorn protease homolog {ECO:0000256|PIRNR:PIRNR036421};
DE EC=3.4.21.- {ECO:0000256|PIRNR:PIRNR036421};
GN ORFNames=B5M54_05420 {ECO:0000313|EMBL:OQX54298.1};
OS Candidatus Aminicenantes bacterium 4484_214.
OC Bacteria; Candidatus Aminicenantes.
OX NCBI_TaxID=1968529 {ECO:0000313|EMBL:OQX54298.1, ECO:0000313|Proteomes:UP000192734};
RN [1] {ECO:0000313|Proteomes:UP000192734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Dombrowski N., Seitz K., Teske A., Baker B.;
RT "Novel pathways for hydrocarbon cycling and metabolic interdependencies in
RT hydrothermal sediment communities.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Degrades oligopeptides. {ECO:0000256|PIRNR:PIRNR036421}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR036421}.
CC -!- SIMILARITY: Belongs to the peptidase S41B family.
CC {ECO:0000256|ARBA:ARBA00008524, ECO:0000256|PIRNR:PIRNR036421}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQX54298.1}.
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DR EMBL; MZGL01000024; OQX54298.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W9P7B1; -.
DR Proteomes; UP000192734; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR CDD; cd07562; Peptidase_S41_TRI; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.750.44; -; 1.
DR Gene3D; 2.120.10.60; Tricorn protease N-terminal domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR005151; Tail-specific_protease.
DR InterPro; IPR028204; Tricorn_C1.
DR InterPro; IPR029414; Tricorn_PDZ.
DR InterPro; IPR012393; Tricorn_protease.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR43253; TRICORN PROTEASE HOMOLOG 2-RELATED; 1.
DR PANTHER; PTHR43253:SF1; TRICORN PROTEASE HOMOLOG 2-RELATED; 1.
DR Pfam; PF07676; PD40; 2.
DR Pfam; PF03572; Peptidase_S41; 1.
DR Pfam; PF14684; Tricorn_C1; 1.
DR Pfam; PF14685; Tricorn_PDZ; 1.
DR PIRSF; PIRSF036421; Tricorn_protease; 1.
DR SMART; SM00245; TSPc; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR036421};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR036421};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PIRNR:PIRNR036421};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|PIRNR:PIRNR036421}.
FT DOMAIN 868..1050
FT /note="Tail specific protease"
FT /evidence="ECO:0000259|SMART:SM00245"
FT REGION 548..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 759
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT ACT_SITE 982
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT ACT_SITE 1039
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
SQ SEQUENCE 1093 AA; 123273 MW; 849328E38CED42A7 CRC64;
MRRQKLRLTL GICVILLCFF PLKAIDVHDT KLLSQPAITQ GKIAFVYAND IWICNWQGKN
VFRLTSHPGV ESNPVFSPDG QWVAFSGEYD GNTDVYLVPV EGGIPKRLTW HPGADIVRGF
TPDSRKVIFI STRNSFTYAH NKLFTISIKG GMPEELPLPY VYKASFSPDG QKMAYVPLRE
AFHQWKHYRG GTVSTIWIIK LSDLSVQKIP QPEGRCNDTD PMWIGDKIYF RSDRAGEFNL
FVYDLSTEKI MQLTHFDDFP VLSVAAGAGK IIFEREGHLF LYDLATNKSE RLVIGVAADL
LELRPRYAQG EKFIRSSAIS PTGARAVLGF RGEIVTLPAK KGDFRNLTNS PGAHDRYPAW
SPDGSQIAFF SDASGEYQLY VISQDGQGPV KKFSLPGAGF YDSLAWSPDS KKLTFADNSW
SLFWIDLETG KVKKIASEYL YGPSEYKSIR GVWSPDSRWV VYTLNTKAYI QKVYVYSLEQ
DKSFPITDGL SEVSEPVFDP SGHYLYFFAS TDAGPVKHWF AMSNADLRMT KAIYLAVLRK
DLPSPLAKES DEEKLEGKEE KKGQEEKEQE SSSKPKEEVV TIDFEGLNQR IVALPIPVGS
YFNLQVAGKG QLYFLEISAS ARGPSRPGAK LHYFDLKARQ DKVLAEGLYS FSLSANGKKL
LYRARNQLGI VATGQKFRPG EGKLNTESIK IKINPQEEWR QIFFEAWRIN RDYFYDPYFH
GIDWPAMKDK YAVFLDHLAC RNDLNRVIQW MCSELGVGHH RVAGGDTLAR TERIPGGLLG
ADFEVDHGRY RFKKVLGGLN WNPELRSPLT EPGVNVRAGE YLLAVEGKEL IPPDNIYRYF
ENTAGKIVEI TVGPFPDGKE ARQVLVVPLA NEYSLRNRDW VEANIRKVDE ATGGRVAYVY
VPNTAGLGYT YFKRYFFPQS HKEAIIVDER FNGGGQVADY YIDILRRPFV CMWAMRYGAD
LKTPSASIQG PKVMLINESA GSGGDLLPWM FRKFKLGKLI GKRTWGGLVG ILGFPVLMDG
GYVTAPNLAI WTEDGWVVEN EGVPPDIEVE QWPALVAQGR DPQLEKAIEV VLEELKKNPP
PQLKRPPYKK INR
//
