ID A0A1W9QVK8_9BACT Unreviewed; 1343 AA.
AC A0A1W9QVK8;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=B6D64_10095 {ECO:0000313|EMBL:OQX76318.1};
OS Bacteroidetes bacterium 4484_276.
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=1970779 {ECO:0000313|EMBL:OQX76318.1, ECO:0000313|Proteomes:UP000192605};
RN [1] {ECO:0000313|Proteomes:UP000192605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Dombrowski N., Seitz K., Teske A., Baker B.;
RT "Novel pathways for hydrocarbon cycling and metabolic interdependencies in
RT hydrothermal sediment communities.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQX76318.1}.
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DR EMBL; NATG01000187; OQX76318.1; -; Genomic_DNA.
DR Proteomes; UP000192605; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF07494; Reg_prop; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 794..811
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 840..1063
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1099..1214
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1245..1343
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT COILED 1203..1230
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1147
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1343 AA; 152652 MW; E79ABC28537147D9 CRC64;
MNKQGNGQEI YNDADFPEKP LYVLTTQNGL PDNFATSAVK DNRGYFWFGT FNGLVKWDGI
TATVFQNIPD DTTSISGNSI SQNALKYNYN ENLLYIGTES GLSIYNLETN RFNNYFVGQP
GPGKLRSGIH SICIDDDSNI WIGTTKGFSE YSPESGSFQN FSYLPTTVDT GIIELVSVNS
VFDIVQDKYH PGTLWIATLE GLIKFDKNSH DMQLFLANGG QYFRETNLMI KLLAHSDGNI
YIGTWNFDLL VFNPKTEKFI DDFGENAPLG DKHIEILPII PFFEKSNHEI WVSSQQGLGV
LDTKADRINF FEVFKNKSGF PYQPFMLFTE NNNTWWIGSD FGLQYFKKQP YSIQNYFFKP
KDITHWYLTL DLTESPASQR LYIGYGRGEG LHYFDLKTND FHVITFAKHG KKEFSIYKII
PDGKNTFLFA TRDEIFRFDE ITSKITPLHL SYSGNPNITD MIRDKKGRVW IAGKNIGIRK
FNPKTGESIS SINWAELFND DALPNIHKVS CDAHGRLWFS RAFGGYGFII PETKEVKHFQ
LPGLHNDIKY FYLTGDTLWA GTSGNGLGFF DPEYPEKGLI MYCNTKNGLE NNYIEGLTRD
KYNRFWLLTG AGLECTGSGM DRSFVVGKNF NLQFRDSRSE KPAFMPGVVY RLANGEIVVG
YRSGLGFLNV DSIKFIHHEV KPYISAIRIF DRPVPPDSLI NQNNEINLAY NENYITLSYS
ALEIDNGSNI ILSHQLQGID IGWKENDNHT AVYSKLAPGN YIFKVKARQT TGYHDISSSQ
YLLYISSPWW ETPWAYTVYV LILFLIIYFI YQILLRRRIN REEIIKLHEL DELKSRLYAN
ITHEFRTPLT VIKGVASEIV ENMTKKEQKI CADKLKMIGR NSDKLLHLVK QMLDMSKIED
GKMKLNLIQD NIVSYLQYVL ESFQSMAGAK NIKLVFYHET DKVVMDYDQD KIFMIASNLL
SNAIKFTLKG GKVIFHVKSE SGQENNNLVI KVQDSGIGIE AQHIQQIFDR FYQIDNSPTR
KGEGTGIGLA LTKELVELMK GEITVKSTPG ERTEFCVTIP ITNRAVLQKS KPARPEPHYT
QETTVSLIAD AGNDNGLPLA LVVEDNADVA KYIISCLKGK YRIKWSPDGG QGIDAAINSI
PDIIISDVMM PVKDGFEVCE TLKQDERTSH IPIVLLTAKA TETDRIEGLS HGADAYLTKP
FNKEELFVRL EQLIKIRQQL QEKYSKVEIT LTEKEQPQGE EIFLKKAIEA IEKQMDNPQF
DPALLAVGLN ISESQLYRKL KALSGKSTSV FIRGIRLSAA KKLLETTTLH ISEIAYQCGF
NNPAWFSRVF KDEFGVSPSG HRK
//
