ID A0A1W9R223_9BACT Unreviewed; 547 AA.
AC A0A1W9R223;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=B6D64_06330 {ECO:0000313|EMBL:OQX78566.1};
OS Bacteroidetes bacterium 4484_276.
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=1970779 {ECO:0000313|EMBL:OQX78566.1, ECO:0000313|Proteomes:UP000192605};
RN [1] {ECO:0000313|Proteomes:UP000192605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Dombrowski N., Seitz K., Teske A., Baker B.;
RT "Novel pathways for hydrocarbon cycling and metabolic interdependencies in
RT hydrothermal sediment communities.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQX78566.1}.
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DR EMBL; NATG01000097; OQX78566.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W9R223; -.
DR Proteomes; UP000192605; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:OQX78566.1};
KW Helicase {ECO:0000313|EMBL:OQX78566.1};
KW Hydrolase {ECO:0000313|EMBL:OQX78566.1};
KW Nucleotide-binding {ECO:0000313|EMBL:OQX78566.1}.
FT DOMAIN 196..352
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 404..547
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 547 AA; 62374 MW; 6E03FF2A8CFA48E5 CRC64;
MPLIVQSDHT LMVEVKHEKY SVCRDFLASF AELEKSPEFI HTYRITPLSL WNAAALDIKI
EEITKGLEGF SRYDIPQNVL ADINDWYSTY GKLTLRPYKN GLLLLEISSK IILERLRHEE
TLTKYWRGSI GKGFLIDLAD RGNIKHDLVK IAYPVKDLCG YVKGDDFELK LRDIDSDGNV
FKLRGYQNEA VEAFYHSGRE TGGNGIVVLP CGSGKTIIGM GAIARISNHT LVVTTNNVAV
HQWRDELISK TDIGPADIGE FTGMDKSIKP ITITTYQMLT YRKSKEDKFH NLDLFTLQNW
GLILYDEVHL LPAPVFRATV GIQAKRRMGL TATLVREDGK EDDVFALIGP KRYDVPWKVL
ENKGFIAEAY CTEYRIAMGE NTEMEYALAN KRGKFRIAAE NQLKIKLVVE LIENHFDDQI
LVIGQYISQV EKIAKDLDIP IITGKTKNEE RETLYNKFRS GELKVLVVSK VANFAVDLPD
ASVLIQVSGT YGSRQEEAQR LGRILRPKKK PSHFYTLVSQ GTTEQDFSIN RQMFLVEQGY
KYEIRYF
//
