ID A0A1W9REG2_9BACT Unreviewed; 568 AA.
AC A0A1W9REG2;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Penicillin-binding protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=B6D53_03700 {ECO:0000313|EMBL:OQX82832.1};
OS Candidatus Omnitrophica bacterium 4484_49.
OC Bacteria; Candidatus Omnitrophota.
OX NCBI_TaxID=1970784 {ECO:0000313|EMBL:OQX82832.1, ECO:0000313|Proteomes:UP000192833};
RN [1] {ECO:0000313|Proteomes:UP000192833}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Dombrowski N., Seitz K., Teske A., Baker B.;
RT "Novel pathways for hydrocarbon cycling and metabolic interdependencies in
RT hydrothermal sediment communities.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OQX82832.1}.
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DR EMBL; NATI01000055; OQX82832.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1W9REG2; -.
DR Proteomes; UP000192833; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 49..181
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 237..541
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 568 AA; 64387 MW; 877216FFE4978B38 CRC64;
MLSINIRKIK IALILLFLVP VMKVGYLQLV KGKYFSKIAE EQQEKVLTIR GKRGDILDRW
GRVLAMDRNV YSIYANPRIV RDKETVAREL ECILGISYEE MMEKLCRNCY FVWLKRGITA
KAVVESIKKF RGLGVKVERR RIYPQGELAC HLLGAVDIDN NGIAGLELFY DEKLRGKSGY
ILTLGDGRNF YLAGFSTDAV PPRNGDTLIL TIDQVIQHYA EQIAEKLYNK YQARRVSIIV
MDPYNGEILA LANRPGYDPN CITSEDIKYM KNFAISEMFE PGSVFKVIAA AALLDQGLVR
LGDKIYCEHG IYKIGRRTLH DYHKYGWLDF RSVVVHSSNI GIAKFCSRIP DEVFYRYLKL
FGIGEKTGID LPGETSGILR SPENWTDYSK ISLAIGQEVA VNTVHLAKMM SIIANGGFDV
KPHVVREMKD AQGMRIWRFN YQPRRLLKYK TVVKLKQILQ RVVEEGTGKW ARSRVYTAGG
KTGTAQKADP VNGGYAPGKY TATFAGFIPA DNPRMVIVVT VDEPHGSHFG GTVCAPAFKE
LGERSLVYMN LTQERRVKNE TERNFVWN
//
