ID   A0A1X0HLU9_9MYCO        Unreviewed;       251 AA.
AC   A0A1X0HLU9;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Precorrin-6A synthase (Deacetylating) {ECO:0000313|EMBL:ORB27280.1};
GN   ORFNames=BST36_00965 {ECO:0000313|EMBL:ORB27280.1};
OS   Mycolicibacterium moriokaense.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=39691 {ECO:0000313|EMBL:ORB27280.1, ECO:0000313|Proteomes:UP000192354};
RN   [1] {ECO:0000313|EMBL:ORB27280.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP105393 {ECO:0000313|EMBL:ORB27280.1};
RA   Tortoli E., Trovato A., Cirillo D.M.;
RT   "The new phylogeny of genus Mycobacterium.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004953}.
CC   -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00005879}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORB27280.1}.
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DR   EMBL; MVIB01000001; ORB27280.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X0HLU9; -.
DR   OrthoDB; 9787471at2; -.
DR   Proteomes; UP000192354; Unassembled WGS sequence.
DR   GO; GO:0043819; F:precorrin-6A synthase (deacetylating) activity; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd11643; Precorrin-6A-synthase; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR012797; CobF.
DR   NCBIfam; TIGR02434; CobF; 1.
DR   PANTHER; PTHR43467; COBALT-PRECORRIN-2 C(20)-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43467:SF1; PRECORRIN-6A SYNTHASE [DEACETYLATING]; 1.
DR   Pfam; PF00590; TP_methylase; 1.
DR   PIRSF; PIRSF036525; CobF; 1.
DR   SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          4..223
FT                   /note="Tetrapyrrole methylase"
FT                   /evidence="ECO:0000259|Pfam:PF00590"
SQ   SEQUENCE   251 AA;  27615 MW;  F4FC1FE2E2058E7B CRC64;
     MTRRIHVIGV GAGDPDYVTA QAVDALNDTQ VFFAMDKGEA KDDLVALRRL ICERFIREPG
     YRFVELPDPP RTRTVPDSPA YRQVVADWHA RRAQVWASAI ENELAPDGVG AFLAWGDPSL
     YDSTLRILET VAAHVDIDYD VIPGITAIQA LTARHRIPLN DVGEPVLITT GRQLRHNGLS
     GSAVVMLDAE CSFLGCPAET RIWWGAFLGT PDELLVAGTV GEVGDRIAEL RADARSRHGW
     IMDTYLLRSA D
//