ID A0A1X0N0X5_9PSED Unreviewed; 870 AA.
AC A0A1X0N0X5;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=peptidoglycan glycosyltransferase {ECO:0000256|ARBA:ARBA00012555};
DE EC=2.4.1.129 {ECO:0000256|ARBA:ARBA00012555};
GN ORFNames=BZK31_21715 {ECO:0000313|EMBL:ORC57023.1};
OS Pseudomonas floridensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1958950 {ECO:0000313|EMBL:ORC57023.1, ECO:0000313|Proteomes:UP000192815};
RN [1] {ECO:0000313|Proteomes:UP000192815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GEV388 {ECO:0000313|Proteomes:UP000192815};
RA Timilsina S., Vallad G.E., Jones J.B.;
RT "Pseudomonas floridae sp. nov., a novel pathogenic bacterial species
RT isolated from tomato.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-
CC Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-
CC (1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-
CC cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-
CC D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl
CC diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+);
CC Xref=Rhea:RHEA:23708, Rhea:RHEA-COMP:9602, Rhea:RHEA-COMP:9603,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58405, ChEBI:CHEBI:60033,
CC ChEBI:CHEBI:78435; EC=2.4.1.129;
CC Evidence={ECO:0000256|ARBA:ARBA00023988};
CC -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004752}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORC57023.1}.
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DR EMBL; MUIO01000093; ORC57023.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X0N0X5; -.
DR STRING; 1958950.BZK31_21715; -.
DR OrthoDB; 8552189at2; -.
DR Proteomes; UP000192815; Unassembled WGS sequence.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3810.10; Biosynthetic peptidoglycan transglycosylase-like; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001264; Glyco_trans_51.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR036950; PBP_transglycosylase.
DR PANTHER; PTHR32282; BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR32282:SF33; PEPTIDOGLYCAN GLYCOSYLTRANSFERASE; 1.
DR Pfam; PF00912; Transgly; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022670};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Transferase {ECO:0000313|EMBL:ORC57023.1}.
FT DOMAIN 2..183
FT /note="Glycosyl transferase family 51"
FT /evidence="ECO:0000259|Pfam:PF00912"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ORC57023.1"
SQ SEQUENCE 870 AA; 96422 MW; B7D7FB63486A8330 CRC64;
LADIPPVVVH SLLFIETRDL LDPQQPMANP AVDWPRFAKA AWSQLARMLS LPGQSAGGST
LATQLEKYRH SPDGLTQSGS EKIRQMISAS VRAYQPGAQT LEVRQHVVRD YLNSVPLSAV
PGHGEVHGLA EGLRVWFGVD FARTNEILAS TPTDKNALAE KALALREVLS LVIAQRRPSH
YLSKGRLELA DLTDSHIRLL ANANVIDQSL ADAALAATVT YRDWVQQPTI QPIETNKGIS
VARTRLSNLL NRPLYDLDRL DLSATSTLHG QLQTQVSQYL RDLANPEFAG SIGLLGERLL
TPASTAQVRY SFTLFERGPD GSRVRVQTDS TDQPFDINEG SKLELGSTAK MRVLTTYLEI
IAELHGRYAG MSVAQLRKVP VEEPDRLTRW CVDYLLQNKD RDLSKMLSAA LDRTYSASPG
EAFFTGGGMH RFNNFRHEDD GRIPTLRESL RESINLPFIR LMRDVVRYST YQAPSNSAAL
LKDDDNPRRQ EYLSQFADRE GTVFLLRFWK RYKDKTTQER LDTFLDGILP TAIRLAAVHR
YLLPGADRST FNAFVRAHLE DTRAITKLTD KRLAELYDGY GPGAYDLPDQ GYVARVHPLD
LWLVGYLLKH PEAQFKDAVA ASRFERQEVY GWLFKSRHKG ARDSRIRTMM EVEAFLDIEQ
RWQRVGYPFD HLVPSLATAI GSSGDRPAAL AELIGIIQND GIRLPAVRID SLHFAADTPY
ETELTVNPEL GQRVLPSEVA AAMREALSQV VDGGTAKRVQ GTFKMQDGSV LAMGGKTGTG
DNRIESIGAG GRIISSRAVN RTATFVFYIG ENHFGTLTAF VPGRAAEGFR FTSALPVQVL
KGMAPILTPY LENNGRAMCN TPSPPSGTGA
//
