ID   A0A1X0NEX4_9TRYP        Unreviewed;      1275 AA.
AC   A0A1X0NEX4;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ORC82983.1};
GN   ORFNames=TM35_000791090 {ECO:0000313|EMBL:ORC82983.1};
OS   Trypanosoma theileri.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=67003 {ECO:0000313|EMBL:ORC82983.1, ECO:0000313|Proteomes:UP000192257};
RN   [1] {ECO:0000313|EMBL:ORC82983.1, ECO:0000313|Proteomes:UP000192257}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Edinburgh {ECO:0000313|EMBL:ORC82983.1};
RA   Kelly S., Ivens A., Mott A., O'Neill E., Emms D., Macleod O., Voorheis P.,
RA   Matthews J., Matthews K., Carrington M.;
RT   "An alternative strategy for trypanosome survival in the mammalian
RT   bloodstream revealed through genome and transcriptome analysis of the
RT   ubiquitous bovine parasite Trypanosoma (Megatrypanum) theileri.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORC82983.1}.
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DR   EMBL; NBCO01000079; ORC82983.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X0NEX4; -.
DR   STRING; 67003.A0A1X0NEX4; -.
DR   VEuPathDB; TriTrypDB:TM35_000791090; -.
DR   OrthoDB; 148480at2759; -.
DR   Proteomes; UP000192257; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.470; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   InterPro; IPR017233; WDR35.
DR   PANTHER; PTHR15722; IFT140/172-RELATED; 1.
DR   PANTHER; PTHR15722:SF8; REPEAT PROTEIN, PUTATIVE-RELATED; 1.
DR   Pfam; PF00400; WD40; 1.
DR   PIRSF; PIRSF037536; WD_repeat_p35; 1.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   SUPFAM; SSF69322; Tricorn protease domain 2; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
PE   4: Predicted;
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192257};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          59..90
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   1275 AA;  143165 MW;  DE606A08845DD18B CRC64;
     MFVYFSKRVA IPTSNVITSI AWNEEQGWLA CGGKGGLLKV LKIDNGAGQK GGLTMNQTLE
     GHTADVSVVA WNHQYRKLTS SDEKGQIIVW MLHKGMWLEE MINNRNKSTV RDLSWNTDGT
     KVCIIYEDGA VIVGGVDGNR LWGKDLKNEL AKVTWSPDDR CILFGTKNGE VHVHDSSSGV
     FMNRVSITCQ TDEAPLAGLS WHPAWVDRPS PLAMLAVCYK SGRMQLMHGT GDAHPYIVDT
     GIPVSCISWN PQGTTLAVCG VTSTSSATNS TSGAAAAGGG ESVPPSTSTS VVVVQFFNAE
     GIHLRSLRVN GNHCGGVTWE GDGLRVAIAI DAALYFANVR PDYKYTYFNK TVVFAYNRPD
     RLEDSVMFWN IRSNERVIRH IRGLFHIDSC KDACMIVNSP DDGRHSIVEL VNAIGSPMET
     RMLEMVPLVC GMNSSHMVVA DEENIYVWQF RDPSVVVDAL DPISVQASRR ETRDRVVHVD
     EIVRPDTPAT LIGHTAVTND LVCALCVSED FLFVARESGL LQLYRFAPLH LVGKIILPVR
     VQFMAANVNS TRLAVVDLAG VLALFHIDPE NLSLVPRKIA PQPNFERKDV WNIQWAQDDP
     EQLVVLEKSR MYIFHGTEAE EPVHSSGYIC KFRSLKVRAL QLDELMQDPE RPRKEYIVDY
     ETRVLRDARQ VIQNVSMKEA FMFIDEHPHP KLWELLAEQA LSQLDFDHAE AAVIRCKDYP
     AIQFVKRVKM LDDPQKQRAE IHAFYHRFDE AEKIYKEIDR KDLALELRYR IGDWFRVVQL
     VQEGGGDESH MQKAWENIGD YYADRQKWTK ASQYYTQCRQ LHKLAHIFFL LEDYELLAQL
     ITNAEHDKEL LLKIGEMLLA VGLGDEASRA FLAAGEPRLA VDGCVQLHMW DRAMSIAESH
     KITDVAPQLG RQAARLVESE RLPEAIELYR KAGQHDEAAR LLARLGQRSA ATDPLRAKKF
     YVLSALEIEK YRRKKMTLSG DGAAAVDALL NAEQKTTSER TLDAAWRGAE AFHFFLLCQQ
     HILCRNLPYA LNAAMRLMDY DDLISPVDSY SLIALTAYLA KNFSICSKAF TRLEAAEQLD
     AQQELQQEGG PVAAGQLQLI DLTLDLDVTN RTRPANRNTK GLTGGTTRLD GTTTSLQLTN
     PSKGMVTATQ FTYPTVSLKE PRRRFADLAV KIFTQYKPED TSVDRVKCPK CEAFNKEWAS
     CCIRCQQPFG VCIFSGRCIV SDDFWQCSVC HHRIIEVDAD RFRNCPLCHT PIKQRSHGRG
     GENTRGDGVT LGYEM
//