ID A0A1X0NKP5_9TRYP Unreviewed; 786 AA.
AC A0A1X0NKP5;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
GN ORFNames=TM35_000361550 {ECO:0000313|EMBL:ORC85295.1};
OS Trypanosoma theileri.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=67003 {ECO:0000313|EMBL:ORC85295.1, ECO:0000313|Proteomes:UP000192257};
RN [1] {ECO:0000313|EMBL:ORC85295.1, ECO:0000313|Proteomes:UP000192257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Edinburgh {ECO:0000313|EMBL:ORC85295.1};
RA Kelly S., Ivens A., Mott A., O'Neill E., Emms D., Macleod O., Voorheis P.,
RA Matthews J., Matthews K., Carrington M.;
RT "An alternative strategy for trypanosome survival in the mammalian
RT bloodstream revealed through genome and transcriptome analysis of the
RT ubiquitous bovine parasite Trypanosoma (Megatrypanum) theileri.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORC85295.1}.
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DR EMBL; NBCO01000036; ORC85295.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X0NKP5; -.
DR VEuPathDB; TriTrypDB:TM35_000361550; -.
DR OrthoDB; 157370at2759; -.
DR Proteomes; UP000192257; Unassembled WGS sequence.
DR CDD; cd00030; C2; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR PANTHER; PTHR39666:SF1; C2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR39666; RANBP2-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00168; C2; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50004; C2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000192257}.
FT DOMAIN 1..111
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REPEAT 687..719
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 143..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..231
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..527
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 82120 MW; B1296007C8B51E5F CRC64;
MSFDGGLQQG RVTLTVHRAE SLVGLNPNGT SNPFVTATIG QQSHSTGVVN SSTNPSYEAT
FNFSPCPLPT ILTLRVYNKV PFTETEELLG SATLTLFSAS PKVRRSVQLG HGGNVALSQK
ARDGSCGSLD ISYEVVLAES QSQLQSQSST QQSAIKDNDL PPFLRDDNGP PNLTSAYAAV
TSTATASSTT ATTSTTSAAP PPPPALTSTV PPPPPPPTAA VPPPPPQLAM PMTPNETIVA
RPPQQSSQGT YQQQQQQQQM QQSTLPPPPP VVSRTPSIVQ QPSQQQQQPI GTSFSGTSTG
NVIPTTNMQN INEPMVRKPS VADTSTAPPM VMPLQQLPVT LPVAHDIDAG KVSNAPSAMY
TEAARVPPVP TGPPMQMMTP YNGGTSSTRE NGINGQTLIN TNNTIQQTVR TTSASTPPSQ
GSSLTTSTSM TPSSTVASNS ILHHQQQQQQ DQQRLQQMQL PTAVVPPPVT SGLTFTSGPP
VLQLSQQQQQ PSVSATAPSA GLPPPPPPLP AAAAAAAAQP PPQPPVATTT IEKDDDKTKK
KVKIIAAPKG RTVSTSATPA TSGRGGVRPM SSTDRTTRNG AASPTRDNRR SLSNNGIRSS
SRGRTHPGSA TVATNSTTTT TIGGMNSLPS SSSGGGLHNN TISGSGLYHQ PDDLLAAAVA
GNTAVFQRLR EEDPLLSRGF EHVRDYSGRT ILHIAAWYGH TDVLKTLLQA SPSIPMLELR
ALRSNNGNTI LHSAAQGGRA AVVQWLRFGH PATGLLVGLR NVRGSTATEC AREAGFNDIA
AMLDEA
//
