ID A0A1X0NSZ0_9TRYP Unreviewed; 963 AA.
AC A0A1X0NSZ0;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Putative C-terminal motor kinesin {ECO:0000313|EMBL:ORC87835.1};
GN ORFNames=TM35_000202440 {ECO:0000313|EMBL:ORC87835.1};
OS Trypanosoma theileri.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=67003 {ECO:0000313|EMBL:ORC87835.1, ECO:0000313|Proteomes:UP000192257};
RN [1] {ECO:0000313|EMBL:ORC87835.1, ECO:0000313|Proteomes:UP000192257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Edinburgh {ECO:0000313|EMBL:ORC87835.1};
RA Kelly S., Ivens A., Mott A., O'Neill E., Emms D., Macleod O., Voorheis P.,
RA Matthews J., Matthews K., Carrington M.;
RT "An alternative strategy for trypanosome survival in the mammalian
RT bloodstream revealed through genome and transcriptome analysis of the
RT ubiquitous bovine parasite Trypanosoma (Megatrypanum) theileri.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORC87835.1}.
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DR EMBL; NBCO01000020; ORC87835.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X0NSZ0; -.
DR STRING; 67003.A0A1X0NSZ0; -.
DR VEuPathDB; TriTrypDB:TM35_000202440; -.
DR OrthoDB; 314559at2759; -.
DR Proteomes; UP000192257; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115:SF191; KINESIN-LIKE PROTEIN KIF9; 1.
DR PANTHER; PTHR24115; KINESIN-RELATED; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Reference proteome {ECO:0000313|Proteomes:UP000192257}.
FT DOMAIN 13..372
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 478..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 577..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 631..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 770..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 882..906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 713..740
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 112..119
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 963 AA; 104372 MW; B136A395C19D6C4F CRC64;
MLTARSYNSM PSQVRIVVRT RPTNFVTNNF HVMSNNTLCI TRPNNGDVST GNATRANTKT
ASPGGTSVEE NLTFTADAIL QDAPQELVYN TAAADLVEAV VQGFNCTLLC HGQSGSGKTY
TLFGGNTYPT RGCVPRAIQA VFDSIKLSSE REFKVSLTFV EVYGEQVYDL LGRGPSAAAV
LAAAAKIGGK ESGNVNKASV TIDTSGAVVL RGVDERVCVS EGEALAAVFE GLQRRLCGAN
PLNPQSSRSH AVLTLYVVSK SLIDSDAVVH HSRCNFVDLA SSDRPYAAGD EAAAQETRVI
NKSLAMLEQV VLALAAHRPR HVPYRQSKLT MLLKDSIGGS SRTTLIANVW PEPRHTEATI
ATLNFAKRMM RVESKPAMHA SMDPEAQIKM LQKQLLSLKA ELRMQDQLAG REAVATAPLE
TDEIQTARER VEAFIEGSIP QVSVTCVREM HACFLAFKSI LEERDTMMKD MEHQLAITTP
RPGSSCSAKS TAKRKYSTRQ NNNSESRETT RYVTSSMDTT TGVGVGSTDK LSPGLREMFQ
QQQRNVSFSA HAGHNTSPGR VSGADYVITS VMDGTVPSTA GTTPATTRAT TSTTTATTVS
PQAITAASQN TMAGSVATSA AVAASKVASS TTNFSTPNDE ELMKGRFYPP TSSYSPAREA
YENTLSPAEQ QASTAPLPSV KGIGRQEGVV RDKRLAFEMY KRTPNGACQL EVINNAQKLV
AEKNEEILRL QQRVQEIKAD MESNKKGQSV GMQRIEERVV SRYATSQTGR VSVDVSEGSD
AVNENNNTTT TTNNNNNNNT NNDNESILAA NLLRASLTED LRNMSATEKK ALLSHTTRAV
TRALTERGVL VKQLNRHREA FMNNFQYWYK SSLQSTILPQ KGKTGTESVG GSDTLPTLKS
VNSSLPTTGT PRVTIFTEGD IRFIDGGEQF EAAEMQRRLQ KDPDGVAFYA AQDLVKKRLS
TRQ
//
