ID   A0A1X0NXI3_9TRYP        Unreviewed;       605 AA.
AC   A0A1X0NXI3;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   22-FEB-2023, entry version 19.
DE   SubName: Full=Putative ribonuclease {ECO:0000313|EMBL:ORC89248.1};
GN   ORFNames=TM35_000132520 {ECO:0000313|EMBL:ORC89248.1};
OS   Trypanosoma theileri.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=67003 {ECO:0000313|EMBL:ORC89248.1, ECO:0000313|Proteomes:UP000192257};
RN   [1] {ECO:0000313|EMBL:ORC89248.1, ECO:0000313|Proteomes:UP000192257}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Edinburgh {ECO:0000313|EMBL:ORC89248.1};
RA   Kelly S., Ivens A., Mott A., O'Neill E., Emms D., Macleod O., Voorheis P.,
RA   Matthews J., Matthews K., Carrington M.;
RT   "An alternative strategy for trypanosome survival in the mammalian
RT   bloodstream revealed through genome and transcriptome analysis of the
RT   ubiquitous bovine parasite Trypanosoma (Megatrypanum) theileri.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CAF1 family.
CC       {ECO:0000256|ARBA:ARBA00008372}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORC89248.1}.
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DR   EMBL; NBCO01000013; ORC89248.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X0NXI3; -.
DR   STRING; 67003.A0A1X0NXI3; -.
DR   VEuPathDB; TriTrypDB:TM35_000132520; -.
DR   OrthoDB; 276176at2759; -.
DR   Proteomes; UP000192257; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR006941; RNase_CAF1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR15092; POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1; 1.
DR   PANTHER; PTHR15092:SF23; PUTATIVE-RELATED; 1.
DR   Pfam; PF04857; CAF1; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000192257}.
FT   REGION          155..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          411..432
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  69507 MW;  AB68019FBAC8D8EA CRC64;
     MQVTRDNFPA IFPKFVELLQ TCDFYSFDEE MTGINTPELP ESMTDSPEES YRAKCTVASR
     YNIIQVGICL FHKDNKNSKS TPTQYIARPF NFILFPNHSD DFTIEERSRD VVLSPSSLAF
     LRRHDMNFQS WIYYGIAYCD KVQEEALRKK HQERYKELSQ NNNNNNNNNN NKDQGIDIMT
     EEEKKWFDNA VSTVRTFSDR IQDTLNRVKE KNKDFPLSKI ELAATMDLLQ SSGREIFLTP
     VKSKTVREYF KQYVEKHFNN VLISFRRQGS SFTGIVRAIF PEERARLEKK EENFKKRELT
     DMLGFRLIFK ALVESEKPCV GHNCFADILF LFASLESSLP DTLPEFKERL GKMFPIIFDT
     RYIASRQDYF PLGRFGSRYL GGFFEEYGFN SANIQVKLPL GFEAYDAMTT EKGERNSSSS
     GSSSGNNNKN NNGLTHEAGY DALLTGTLLL NLLAEMGGYD VATAPKNVIN RVALFRSLYA
     LRLDDLKEDE YLPENGVLEL RHEKNIKVHH IESCFLTLSF QNVSLYTIDE TRTLAVLPSS
     WSKSPTLVGE NKDAKWLSTF ITSRFPQYFE ASLYDPARNK PGMGVGPFRT TPKALMRAAL
     KAALR
//