ID A0A1X0P1D2_9TRYP Unreviewed; 960 AA.
AC A0A1X0P1D2;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 28-JUN-2023, entry version 21.
DE SubName: Full=Putative CAS/CSE/importin domain protein {ECO:0000313|EMBL:ORC90715.1};
GN ORFNames=TM35_000071390 {ECO:0000313|EMBL:ORC90715.1};
OS Trypanosoma theileri.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=67003 {ECO:0000313|EMBL:ORC90715.1, ECO:0000313|Proteomes:UP000192257};
RN [1] {ECO:0000313|EMBL:ORC90715.1, ECO:0000313|Proteomes:UP000192257}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Edinburgh {ECO:0000313|EMBL:ORC90715.1};
RA Kelly S., Ivens A., Mott A., O'Neill E., Emms D., Macleod O., Voorheis P.,
RA Matthews J., Matthews K., Carrington M.;
RT "An alternative strategy for trypanosome survival in the mammalian
RT bloodstream revealed through genome and transcriptome analysis of the
RT ubiquitous bovine parasite Trypanosoma (Megatrypanum) theileri.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the XPO2/CSE1 family.
CC {ECO:0000256|ARBA:ARBA00008669}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORC90715.1}.
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DR EMBL; NBCO01000007; ORC90715.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X0P1D2; -.
DR STRING; 67003.A0A1X0P1D2; -.
DR VEuPathDB; TriTrypDB:TM35_000071390; -.
DR OrthoDB; 178772at2759; -.
DR Proteomes; UP000192257; Unassembled WGS sequence.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR005043; XPO2_C.
DR InterPro; IPR013713; XPO2_central.
DR PANTHER; PTHR10997:SF8; EXPORTIN-2; 1.
DR PANTHER; PTHR10997; IMPORTIN-7, 8, 11; 1.
DR Pfam; PF03378; CAS_CSE1; 1.
DR Pfam; PF08506; Cse1; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000192257}.
FT DOMAIN 33..107
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 960 AA; 107438 MW; 387394C49E59C28C CRC64;
MHAIDPNDPV LAQRLVKLAS DAVSMNNSDR EKAEHEIKEF QNSVDKQTGF VLLLLNVAVA
SGPASSFCSI VFKNTVKTCW DAATAEHCIT ENDKAVVRDT ITLLMLRAPP NVQRNLAEAI
TMIAEIDFPE KWPNALDRIV QSLMNEKDVA IQSAALSTAH SILGRYRSQT DLSEKLAEDL
RIIYTTLTSP LLLSMEYLLG EMEKCNSSFK AACQGLTSAV ECLRDMTTLD LGDEFIWNLN
KFVDVLMRCL QFSSPVTDDM VLIELKSAVM ACVTHFLLRF DEDFEKHAGG FMNVVWNTIA
SPSSRSSAMD DVVIQGINLL SAACRGSMRT VFDNTEVLEN LVVQVILPNL ALQTEDIELY
ERESDEYIQR DIEGSDLHTR RREAGELVRS LMVSFPDKSG PLFTAQLQHL MTAVASGDWK
AKDLSIYLVS ALALEGQYAN TQRGASQQLS GLVPFESFLR HNILTELSSD VSSQSPFIIK
ADCIRFVATF RAHIDPQIIP DVVALLTSWI RCPDEVVHAY AAHAVERILT VRRPGQQELI
ISDANMGDKV APLLQHLCMR LQQDKRPCAY TMQCLLRVSQ NCSHSVKPFV GDIITCIAPV
VQSNAKNPSN PLFSHCMFEV ISKCIQLRPE DAAAIEGALW EPMIFILQND VLEYVPYTLQ
IMAQLLDTRS GGSPDPPAHY QALLEPLLVP DMYQQKGNIP AVVRLLVSFI EHYPRYVHSK
GLTEKTLMIF RALLQYKNYD HEGFNILTSM VIAYPKDIIE PFMGSVYQAL FQRLQTSRTP
KYVRILIIFL SIVVVVHGAN DVVTRINLIQ NGLFWMLLQR VWLPNVQKIL GPLERKVCVV
ALSCLLGECE ELQQNSEVWT SCVVTCLKMI HGAVENDDVT SFTPKAHTMG DLKQYVDDSG
FTNIFCPLQG AVRPPIDVCA SVKQPHVYFR ERVQQALRGP NGAHLEGLLR ANHELWAAVQ
//
