ID A0A1X0Q9Y6_9MICR Unreviewed; 1120 AA.
AC A0A1X0Q9Y6;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=SMC4 {ECO:0000313|EMBL:ORD96525.1};
GN Name=SMC4 {ECO:0000313|EMBL:ORD96525.1};
GN ORFNames=HERIO_1546 {ECO:0000313|EMBL:ORD96525.1};
OS Hepatospora eriocheir.
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Hepatosporidae;
OC Hepatospora.
OX NCBI_TaxID=1081669 {ECO:0000313|EMBL:ORD96525.1, ECO:0000313|Proteomes:UP000192356};
RN [1] {ECO:0000313|EMBL:ORD96525.1, ECO:0000313|Proteomes:UP000192356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GB1 {ECO:0000313|EMBL:ORD96525.1,
RC ECO:0000313|Proteomes:UP000192356};
RX PubMed=28345194; DOI=10.1111/1462-2920.13734;
RA Wiredu Boakye D., Jaroenlak P., Prachumwat A., Williams T.A., Bateman K.S.,
RA Itsathitphaisarn O., Sritunyalucksana K., Paszkiewicz K.H., Moore K.A.,
RA Stentiford G.D., Williams B.A.;
RT "Decay of the glycolytic pathway and adaptation to intranuclear parasitism
RT within Enterocytozoonidae microsporidia.";
RL Environ. Microbiol. 19:2077-2089(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC4 subfamily.
CC {ECO:0000256|ARBA:ARBA00006005}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORD96525.1}.
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DR EMBL; LVKB01000081; ORD96525.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X0Q9Y6; -.
DR VEuPathDB; MicrosporidiaDB:A0H76_1445; -.
DR VEuPathDB; MicrosporidiaDB:A0H76_2537; -.
DR VEuPathDB; MicrosporidiaDB:HERIO_1546; -.
DR Proteomes; UP000192356; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR18937:SF172; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 2.
DR PIRSF; PIRSF005719; SMC; 2.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000192356}.
FT DOMAIN 466..576
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 171..261
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 303..387
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 652..829
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 941..968
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1120 AA; 131688 MW; A34EEEA5D99339DF CRC64;
MTSQSLQIEY VTLKDFKSYK GEYRIGPFDK HFTAIVGPNG SGKSNIIDGI LFVLGYKAKK
MRNSSISALI NHECTSCSVT IEFNNLHIMR IAEKNNTSKY FIKDTNKSNS FKSIPFAKLS
TLLKEEYNID LDHNRFLILQ GEIESIAMMG SMELLAYIED CIGSSKYIKV IEENENNIVD
CKQKLVRYES EIEFYENDYK FKKTKREEKI VVLNMKMTLN DLQMKIVCVK EEQAKRDLEL
LKEEQEKLKN ILENINYEIK QNLDSVDVNN ILQVDKELEK RYYEERMKYN QMMRASEINK
NKIEMLLEEI TEVENSKKEK DNLKDKIKEF MVNLESFQKS KLKLEGELSN LNTNKHSTQL
NEFNKTKKDL KKELMIMIDK QNKYEKNLTV QEENIKRKKL IEIEIKKLQN LKSCNITEEQ
LNDYLKDKEA TLREIRIRKQ NAYEFKYLEN QYKKEKEVIN NIKHVNGYLG PLKTFNNVDK
EYEVAVEAAC TSLNSIVVET SKSAEEMIKI INSKNLQRTT FIILDKIDKK YNYNKQHEEY
LLFKKINCEE RFEPCFYFAL RDTLVVDDIK TARSLAFGKN RNRVVTKDGK LLEKSGIMSG
GKKVGKIKST VELEEIVKDI QMKYDKENSI YQEYKTSGIR IKELKKELDK IKEINVQEYV
NYEEEIEKVK SKLLNLENKL PEELKEHNKR CKDLENELSK INNSIFELQL KISEHQGKLN
LTKNHKNLKN LKKEYEDLLN KNNFSCQIDK TKYEEIKKEY EEMIDRVDKH NKEIKECRER
MDKLVKEQIQ IKYDANVLKN KKSEGKKVLN ICENTLAKLI EEVERIKEVL SYGSIDFENI
SNIEERNNCK IKKYDVINKS KEINIKEVVN EVKEQFSMES DLKTLSVNYI NQYNNETSEC
KKLLNEKFKV TEEELIQSFC KDSYLLYKSI FVDFIKSKEK FNKVKSNFDR TTLKLKELQN
ELEEIKNNRL TEFLSGFNII NRHLKKIFSN ITFGGNAELD LLNYLDPFSD GLSLNVLPPK
KSWKAVSSLS GGEKTLSSLS LIFALHKYKP SSFYIMDEID AALDYRNVSI ISQYVSRISS
QFIIISLRND MFEKAQVLVG VYKNGDVSKF ITCDVRKMKN
//
