ID A0A1X0UQQ0_9NOCA Unreviewed; 2734 AA.
AC A0A1X0UQQ0;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=BJI47_08630 {ECO:0000313|EMBL:ORI23159.1};
OS Rhodococcus sp. 1168.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=2018041 {ECO:0000313|EMBL:ORI23159.1, ECO:0000313|Proteomes:UP000192546};
RN [1] {ECO:0000313|EMBL:ORI23159.1, ECO:0000313|Proteomes:UP000192546}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1168 {ECO:0000313|EMBL:ORI23159.1,
RC ECO:0000313|Proteomes:UP000192546};
RA Nahar A.;
RT "Metabolic and lipid synthesis pathways analysis of sub-Antarctic
RT Rhodococcus luteus.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORI23159.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MKKY01000039; ORI23159.1; -; Genomic_DNA.
DR UniPathway; UPA00011; -.
DR Proteomes; UP000192546; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR CDD; cd19543; DCL_NRPS; 1.
DR CDD; cd19540; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 3.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45398; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR PANTHER; PTHR45398:SF1; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 3.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 3.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000192546}.
FT DOMAIN 349..424
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1404..1478
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2734 AA; 291532 MW; 5297BF2F010C7D02 CRC64;
MAVSHEAVVN QLVWKRSEFG LGVGDVVLLK TAATFDLSVW EFWSALVSGA AVVVASVEGH
RDAAYLHELM VAESVTTLHV VPSMLSALLA VSGGVLSSSL VRVLAIGEAL PGATAQWFRR
GNAGALFNLY GPTEAAVSVT VHEVGAGDVA GVPIGVPEWN TGVLVLDERL HPVPVGVSGE
LYLAGVQLAR GYVGRVDLTA ERFVANPFVG VAGVGVGSRL YRTGDVVRWG GSGELEYVGR
SDFQVKVRGF RIELGEIESA LRGVDGVVDV AVVARVDEFA GDQLVAYVVG GVGVSLDVGE
VKVALGAVVP SYMVPSAFVV LDALPLTVNG KLDRAALPAP VFEAVVFRAP STPVEEAVAR
VFSEVLGVDR VGVDDDFFAL GGNSLIATQV VSRLGVALDA VVPVRLVFEA PSVGGLAVRV
EQSVGSGDRV ALVARERPGV VPLSLAQQRM WFLNRFDTES AVNNIPVAVR LSGALDIDAL
NAAVRDVLAR HESLRTVYPE TDGIAAQVIL TVLAAAPTLV PRQVDQADIS RRVEQVISAG
FDVTSELPMR GELFQVGADE YVLVLVAHHI SADGWSMGPL TRDVMVAYAA RSAGEAPGWA
PLPVQYADYA LWQRELLGSE DDPDSIASQQ VSYWKSALAG LPDELNLPTD RSRPSIRTYE
GGKVPFRIDA ELHRALLDVA RTTGSTLFMV VHTAMAVFLA RMSGTDDIAI GAPIAGRGQS
ELDDMVGMFV NTLVLRTHVE SERSFAEILA RAKEADLQAF AHADIPFERL VEVLNPERST
TRHPLFQVAL SFENLPSTDL QLPNLHVSGV PFEANIAKFD LSLTLREHVL AGGDLDGISA
EFSYATDMFD ESTISGFAVR FVRLLDDAVA DLSKPVGDLA LLGAGEAGAL THAHGGAVAS
ASTLQEILTG GVALDPDAVA VRISGRSVTY RELDETSSQF ARVLIGRGVG PDTVAALAFS
RSYEMLVSVW AVAKAGGAHL PVDPNYPSER IEHMLSDSAA VVRITASAHL AALPAGSWML
LDGDELREEI AAQSSDPVTD SDRTATLTTD HPAYVIYTSG STGLPKGVVV THASLRGVLD
SAIDLYGVSP ESRFLHICSP SFDPSVLEWM VAFAAGARLV IVPSDVIGGP DLAEILVSEK
VTHSIITPAV LGTMDPEGMD NLRVLSVGGD VTTAELLARW APGRRYFNGY GPTETTIISS
FAELEPGRPV TIGAPVRGTS ALVLDRRLRP VPAGVAGELY LAGEGLARGY HQRGSLTATR
FVADPYSSTG ARMYRTGDLV RWTGPEVREL EFVGRSDFQV KIRGFRVELG EVDAALAAHP
SVAFSATLGK DLPSGATVLV SYVMPAVGAS VDPVAVTEFV RRTLPSHMVP SSIVILDEVP
LTPVGKLDRR ALPEPVFEEQ AYRAAETEIE EIIAEVFADV LRVPRVGVDE SFFALGGDSI
VSIQLVSRAK ARGVSFTPRD VFERKSVSGL AEVAVRLEDA DRATVLSELP GGGVGSMPLT
PIMHKVTEAG GRLDRFSQSV SVGLPAEIDM ALLTATLTAI VDHHDMFRAA YANGEMAVRE
QGSVDVGAAI DRVRVDGSIS GADLEALASD RLSAAMGRLN PATGAMIQFV WFDFSTGTPT
AGDTDTVEES RRGVLLIVAH HFVVDGVTWR ILLPDLAVAW SQLAAGQQVS LPVVGTSMRR
WSHGLIQAAA VPSRRQELPI WKSLANFDDP LVGRRPFDPT VDVAGTVERV EVEVSAATTD
ALLTRVPRLY RGGVNDGLLA TLALAVARWR RDRGISTTSA LFALEGHGRE EAVVPGADLS
RTIGWFTSAY PLALDLDGID IDDAFAGGAT VGAVVKTVKE QIHRVPDRGM GYGLLKYLDD
ETAAELETVP SGQISFNYLG RISSAEIPAE LADFGWAPTG ALGSLTASMD EDMPANSTID
INAIVTDGPD GPRLGATFAF PNGLVDRADV SELAALWTEA MEALSGHSRT AEAGGLTPSD
LTLIESTQDE IDSWESAYRG VEDVWPLTPL QSGLLFHAMM TESTVDVYTM QAVLDLSGVV
DTDRLRASGQ ALLDRHSNLR AAFVSDSDGR PVQVVLGALE LPFDEIDLMD VAEDSRRAEA
KRILVAAQAE RFDMSAPPLI RFTLIKVAAD AWHLGITSHH ILLDGWSMPL LMQDLLMLYA
VRADTSVLPR VRPFRNFLSW LDGRDREDSL DRWAAAFHGV SEPTLLTESA RPSGAVPGIG
KIEVSLSEER TAVLTAMASN LGVTVNTVVQ AAWGILLGRL TGRADVVFGA TVSGRPADLA
GVESMVGLFI NTLPVRVDVG DGHSRAETLM QLQGQQADLL DHHYVGLTEI QQRIGVDRLF
DTLLVFESYP IDRDAIAAAS SVDGLQITGV GVDDATHYPL TVLTVVEARL ELTFKYLDTV
LDGRYVTDLS RWFLRILDAM IDDPTARVGT IDLLDANERE QVVMASTDLD SGTQGARRSV
GSDMQVLPQV LAEIVEDDPE APAMVSGEDE ISYRVLDVAS SRLARSLIDR GVGPGMSVVV
HLPRSTTAIE ALWAVAKTGA AVIPSQPGAH SSVAEGTFGV TVEQYRDTAP AGPTWLVVDD
PEFARETASR PRHPVSYSDR LQSLSGDHTA LTLSSGSLSQ SELMLRIAEY ADRFELGYDA
RSFHYGSFDS DASIFEAFAV TSRGGALIMG EPDVASVADL LFDSWATHAF VPIEVLEQSG
PEDLDDLVVV IVTDGPATGD AVEVWTDGRT VTHM
//
