ID A0A1X1BMB2_9APIC Unreviewed; 342 AA.
AC A0A1X1BMB2;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Transcription elongation factor 1 {ECO:0000313|EMBL:ORM41232.1};
GN ORFNames=BXIN_0863 {ECO:0000313|EMBL:ORM41232.1};
OS Babesia sp. Xinjiang.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Babesiidae; Babesia.
OX NCBI_TaxID=462227 {ECO:0000313|EMBL:ORM41232.1, ECO:0000313|Proteomes:UP000193856};
RN [1] {ECO:0000313|EMBL:ORM41232.1, ECO:0000313|Proteomes:UP000193856}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinjiang {ECO:0000313|EMBL:ORM41232.1,
RC ECO:0000313|Proteomes:UP000193856};
RX PubMed=27784333; DOI=10.1186/s13071-016-1846-1;
RA Guan G., Korhonen P.K., Young N.D., Koehler A.V., Wang T., Li Y., Liu Z.,
RA Luo J., Yin H., Gasser R.B.;
RT "Genomic resources for a unique, low-virulence Babesia taxon from China.";
RL Parasit. Vectors 9:564-564(2016).
CC -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC of proper chromatin structure in actively transcribed regions.
CC {ECO:0000256|ARBA:ARBA00003357}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ELOF1 family.
CC {ECO:0000256|ARBA:ARBA00009730}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORM41232.1}.
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DR EMBL; MBFZ01000031; ORM41232.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1BMB2; -.
DR VEuPathDB; PiroplasmaDB:BXIN_0863; -.
DR OrthoDB; 276470at2759; -.
DR Proteomes; UP000193856; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.20.25.190; -; 1.
DR InterPro; IPR007808; Elf1.
DR InterPro; IPR038567; T_Elf1_sf.
DR PANTHER; PTHR20934:SF0; TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG; 1.
DR PANTHER; PTHR20934; UNCHARACTERIZED; 1.
DR Pfam; PF05129; Elf1; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:ORM41232.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:ORM41232.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193856};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 191..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 85..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..108
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 38125 MW; CEDFD1E85C48621B CRC64;
MAKRKTKKVQ LSRTQLMQKR RGKLEKEFLC YYCQHEKSVA IKIDNQSGVG LLSCRICGVK
FSTRVTVLDE AVDVYSLWMD SCREGQHAEG TPPKEDDEPF RSQHRSMETI RHTSPTPVSA
PPISQISGVR ADATPANSES HSNANAEYIR PRYLDNETTF TELTTLTGAS RSKNNGRLIY
TSWFACHLNK ILLLFVSVVK FYLTFTVLDV VVSIDALWIY SCYEVQQDES TPTQTVDAPL
RSQHRSVETI IHAAPTPVSA PPISQISGVR ADATPANSES HSNANAEYIR PRYLDNETTF
TELTTLTGAS RSKRIIDAAD DTISGPELVA GTLTRDSLFE ED
//
