ID A0A1X1D785_9GAMM Unreviewed; 397 AA.
AC A0A1X1D785;
DT 05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Glutathione-dependent formaldehyde dehydrogenase {ECO:0000313|EMBL:ORM72506.1};
GN ORFNames=HA48_14215 {ECO:0000313|EMBL:ORM72506.1};
OS Pantoea wallisii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Pantoea.
OX NCBI_TaxID=1076551 {ECO:0000313|EMBL:ORM72506.1, ECO:0000313|Proteomes:UP000193104};
RN [1] {ECO:0000313|EMBL:ORM72506.1, ECO:0000313|Proteomes:UP000193104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 26277 {ECO:0000313|EMBL:ORM72506.1,
RC ECO:0000313|Proteomes:UP000193104};
RX PubMed=28255640;
RA Palmer M., Steenkamp E.T., Coetzee M.P., Chan W.Y., van Zyl E.,
RA De Maayer P., Coutinho T.A., Blom J., Smits T.H., Duffy B., Venter S.N.;
RT "Phylogenomic resolution of the bacterial genus Pantoea and its
RT relationship with Erwinia and Tatumella.";
RL Antonie Van Leeuwenhoek 0:0-0(2017).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORM72506.1}.
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DR EMBL; MLFS01000040; ORM72506.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1X1D785; -.
DR STRING; 1076551.HA48_14215; -.
DR OrthoDB; 9773078at2; -.
DR Proteomes; UP000193104; Unassembled WGS sequence.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08283; FDH_like_1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 8..385
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 397 AA; 42813 MW; E0258D12055A3A28 CRC64;
MKALTYHGPH RVRVETVPDP ILEQPDDIIL RVTATAICGS DLHLYRGKIP GTDHGDIFGH
EFMGEVVEAG RDVTNVQIGD RVVVPFVIAC GDCFFCHLHQ YAACETTNSG RGAILNKKNI
TAPAALFGYS KLYGGVPGGQ AEYVRVPKAN TGPFKVPLTL PDDKVLFLSD ILPTAWQAVQ
NAGLDKGSSV AIFGAGPVGL LSAACARLAG AEEIFMIDHN AYRLDFARQR YGVIPINFDE
IDDPAAWIID HTKGNRGVDA VIDAVGFEAK GSLTETVLSN LKLEGSSGKA LRQCIAAVRR
GGVVSVPGVY AGFIHGFMFG DAFDKGLTFK MGQTHVQAYL PRLLSLIEQG LLTPEEIVTH
HMPLEDAARG YEIFEKRKED CRKVILVPGM ASTTPAV
//
