ID   A0A1X1MRT1_9VIBR        Unreviewed;       436 AA.
AC   A0A1X1MRT1;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Multidrug resistance protein NorM {ECO:0000256|ARBA:ARBA00013489};
DE   AltName: Full=Na(+)/drug antiporter {ECO:0000256|ARBA:ARBA00030855};
GN   ORFNames=ST37_12365 {ECO:0000313|EMBL:ORT49807.1};
OS   Vibrio sp. qd031.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=1603038 {ECO:0000313|EMBL:ORT49807.1, ECO:0000313|Proteomes:UP000193432};
RN   [1] {ECO:0000313|EMBL:ORT49807.1, ECO:0000313|Proteomes:UP000193432}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=qd031 {ECO:0000313|Proteomes:UP000193432};
RA   Xiang T., Song Y., Huang L., Wang B., Wu P.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ORT49807.1, ECO:0000313|Proteomes:UP000193432}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=qd031 {ECO:0000313|Proteomes:UP000193432};
RA   Chen G.;
RT   "Denovo assembling a bacteria genome.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ORT49807.1}.
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DR   EMBL; JXQD01000025; ORT49807.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1X1MRT1; -.
DR   STRING; 1603038.ST37_12365; -.
DR   OrthoDB; 9806302at2; -.
DR   Proteomes; UP000193432; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd13134; MATE_like_8; 1.
DR   InterPro; IPR002528; MATE_fam.
DR   InterPro; IPR048279; MdtK-like.
DR   InterPro; IPR047135; YsiQ.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR42925; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR   PANTHER; PTHR42925:SF1; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR   Pfam; PF01554; MatE; 2.
DR   PIRSF; PIRSF006603; DinF; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193432};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        34..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        154..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        177..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        401..423
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   436 AA;  47617 MW;  B1C744F162100542 CRC64;
     MNIVALTWPI FIEMLLRNTL NMTDVFMLSG YSDLAVSAVG VITPITFFII IISMMVSTGT
     GILIAQNNGA NQPEKSKQVA AASIGLGVLV SLLMGLLFFT QTDNIVSFFG LDPQVHTYAY
     QYLIISGSLS GFVTMSVVFS TVLRSYGNTR SPMVVNLVFG VINVIGNYMV LFEPFGIPVY
     GVTGVACVTV TTQLLGAICF WVLLKKRNLA PTLSEILSAP KTTIKSILRI GVMNAGEVLF
     YNLAQMVIVY FVVQMGTASL TAYTYAQNIA RVGFTFSVAL GQASQIQTSY FVGKGWIEEI
     TGRVKRYFVV GFFVSIVISS TFYLLHKPIL SIFTQDPEVI AIAASLMLAS ILLEGGRVFN
     LIFISSLKGA GDVKFPVQIG IVSMWGLGVG LTYVFGIHFE LGVIGAWFAI AADEWVRGLI
     MALRWRSNVW TRFKLV
//