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Database: UniProt
Entry: A0A1X1QFI9_9GAMM
LinkDB: A0A1X1QFI9_9GAMM
Original site: A0A1X1QFI9_9GAMM 
ID   A0A1X1QFI9_9GAMM        Unreviewed;       743 AA.
AC   A0A1X1QFI9;
DT   05-JUL-2017, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2017, sequence version 1.
DT   05-JUN-2019, entry version 11.
DE   RecName: Full=Ribonuclease R {ECO:0000256|HAMAP-Rule:MF_01895};
DE            Short=RNase R {ECO:0000256|HAMAP-Rule:MF_01895};
DE            EC=3.1.13.1 {ECO:0000256|HAMAP-Rule:MF_01895};
GN   Name=rnr {ECO:0000256|HAMAP-Rule:MF_01895};
GN   ORFNames=A6F71_02990 {ECO:0000313|EMBL:ORU89947.1};
OS   Cycloclasticus sp. symbiont of Poecilosclerida sp. M.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Piscirickettsiaceae; Cycloclasticus.
OX   NCBI_TaxID=1840537 {ECO:0000313|EMBL:ORU89947.1, ECO:0000313|Proteomes:UP000193579};
RN   [1] {ECO:0000313|EMBL:ORU89947.1, ECO:0000313|Proteomes:UP000193579}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Specimen M {ECO:0000313|EMBL:ORU89947.1};
RA   Rubin Blum M., Dubilier N.;
RT   "Short-chain alkanes fuel the metabolism of mussel and sponge
RT   Cycloclasticus symbionts from deep-sea gas and oil seeps.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: 3'-5' exoribonuclease that releases 5'-nucleoside
CC       monophosphates and is involved in maturation of structured RNAs.
CC       {ECO:0000256|HAMAP-Rule:MF_01895}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to
CC         yield nucleoside 5'-phosphates.; EC=3.1.13.1;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01895,
CC         ECO:0000256|SAAS:SAAS01124678};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01895,
CC       ECO:0000256|SAAS:SAAS00089931}.
CC   -!- SIMILARITY: Belongs to the RNR ribonuclease family. RNase R
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_01895}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ORU89947.1}.
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DR   EMBL; LWTN01000235; ORU89947.1; -; Genomic_DNA.
DR   Proteomes; UP000193579; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008859; F:exoribonuclease II activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01895; RNase_R; 1.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR040476; CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR013223; RNase_B_OB_dom.
DR   InterPro; IPR001900; RNase_II/R.
DR   InterPro; IPR022966; RNase_II/R_CS.
DR   InterPro; IPR004476; RNase_II/RNase_R.
DR   InterPro; IPR011805; RNase_R.
DR   InterPro; IPR022967; S1_dom.
DR   InterPro; IPR003029; S1_domain.
DR   Pfam; PF17876; CSD2; 1.
DR   Pfam; PF08206; OB_RNB; 1.
DR   Pfam; PF00773; RNB; 1.
DR   Pfam; PF00575; S1; 1.
DR   SMART; SM00357; CSP; 1.
DR   SMART; SM00955; RNB; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF50249; SSF50249; 4.
DR   TIGRFAMs; TIGR00358; 3_prime_RNase; 1.
DR   TIGRFAMs; TIGR02063; RNase_R; 1.
DR   PROSITE; PS01175; RIBONUCLEASE_II; 1.
DR   PROSITE; PS50126; S1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000193579};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01895,
KW   ECO:0000256|SAAS:SAAS00462075};
KW   Exonuclease {ECO:0000256|HAMAP-Rule:MF_01895,
KW   ECO:0000256|SAAS:SAAS00089915};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01895,
KW   ECO:0000256|SAAS:SAAS00446781};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_01895,
KW   ECO:0000256|SAAS:SAAS00462054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000193579};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_01895,
KW   ECO:0000256|SAAS:SAAS00462035}.
FT   DOMAIN      641    722       S1 motif. {ECO:0000259|PROSITE:PS50126}.
FT   REGION        1     20       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1X1QFI9}.
FT   REGION      722    743       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1X1QFI9}.
FT   COMPBIAS    729    743       Basic. {ECO:0000256|MobiDB-lite:
FT                                A0A1X1QFI9}.
SQ   SEQUENCE   743 AA;  82872 MW;  C9D5F746252F17B1 CRC64;
     MSKNKKPKIT KNDDAGETQD GVSLEKSTVL DFLVEQKTPQ NWPNLVDGLG LRSKKSHKKL
     TRILKGFESA GQIIVNRKGQ YCVTDQAGLI TGTIIGHANG FGFLKRDGGG DDLFLPPKQM
     RLAMDGDRVV ASEGGVNRQG KVEGRIVEIL ERKVCTVVGR FFEKMGSFHV EPENKRINHN
     VFIPAELTQG AKQGQIVLAE ITHYPNIRMQ TIGKVVEIMG DHMAPGMEID VAIRAHDLPH
     QWSQVVLSEA QGFSVDVLAQ DVEGRKDLRK LPLVTIDGAD AKDFDDAVYC KPDSKGWTLY
     VAIADVAHYV RPSSALDTEA IERGTSVYFP GQVLPMLPEV LSNGLCSLKP KVDRLCMVCE
     VHIDPQGQLS NAQFYEAVMH SHARLLYDEV GGILDGSDQQ AKQKHAALIP HLKNLHDLYA
     VLKKASVNRG ALDFDTVETQ FEFDEERKIK AITPVVRHDA HKLIEVCMIA VNSAAARFLI
     ERKIPLLLRV HEGPGIEKLL KLREFLSELG LSLEGGEEPK PAHYKALMEK VKDRPDSHLI
     QMAVLRSMSQ AIYSPEEEGH FGLAIDRYAH FTSPIRRYPD LLVHRGLKHA IKGSSAKKFS
     YSAGDMAELG EHCSYNERRA DEATRDVTSW LKCEFMLDKV GQEFKGVVSS VTSFGLFVEL
     EGTYVEGLVH VTALGDDYYQ YDAAQHRLLG ERSRRSFRMG DELSVELISV NLDEKKIDLA
     LTGASTQKPS RKKRTKHSKS KRR
//
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